Abstract

PORTELA-MARQUEZ, MA et al. Phenolic compounds, antihemolytic, anti-inflammatory and antibacterial activity of propolis from southern Sonora. Biotecnia [online]. 2022, vol.24, n.3, pp.77-86.  Epub June 19, 2023. ISSN 1665-1456.  https://doi.org/10.18633/biotecnia.v24i3.1746.

Propolis is a resin made by Apis mellifera bees from vegetation exudates. Biological properties have been documented. This study evaluated the antioxidant, anti-inflammatory and antibacterial activity of ethanolic extracts from southern Sonora, Mexico propolis. The concentration of total phenols and flavonoids was measured. Antioxidant activity was measured and antihemolytic and anti-inflammatory activity of human erythrocytes was determined. In addition, the activity against Escherichia coli O157:H7, Escherichia coli O157, Staphylococcus aureus and Salmonella typhimurium bacteria was evaluated. The ethanolic extracts presented concentrations of 16.36 ± 1.93 mg EAG/gPS and 42.96 mg EQ/gPS of phenols and flavonoids, respectively. The DPPH and ABTS radicals showed values of 75.65 ± 3.76 and 29.61 ± 0.01 mg ET/gPS respectively, the extracts protected up to 49.56% from hemolysis and prevent cell inflammation up 49%. They also presented antibacterial activity against all the strains evaluated, showing inhibition halos of 8 to 11.3 mm and MIC of 1 and 2 mg of extract/mL. The results are the basis for the study of natural formulations with propolis from southern Sonora.

Keywords : Propolis; antioxidant; antimicrobial; antiinflamatory.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )