Abstract

PENA-VELEZ, Rubén  and  ALMANZA-MIRANDA, Enory. Autoimmune hepatitis in the pediatric age. Bol. Med. Hosp. Infant. Mex. [online]. 2017, vol.74, n.5, pp.324-333. ISSN 1665-1146.  https://doi.org/10.1016/j.bmhimx.2017.05.004.

In pediatrics, autoimmune hepatitis and sclerosing cholangitis are liver disorders with an immunological damage mechanism.

Autoimmune hepatitis is a disease of unknown etiology characterized by interface hepatitis, hypergammaglobulinemia, circulating autoantibodies and a favorable response to immunosuppression. It is an eminently pediatric disease with a prevalent condition in young women. Therapy should be instituted promptly to prevent rapid deterioration, promote remission of disease and long-term survival. The persistent lack of response or lack of adherence to treatment results in terminal liver failure; these patients, and those with fulminant hepatic insufficiency at the time of diagnosis, will require liver transplantation.

Keywords : Autoimmune hepatitis; Chronic liver disease; Seronegative hepatitis.

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