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Revista mexicana de anestesiología
Print version ISSN 0484-7903
Abstract
SANTIAGO-LOPEZ, Janaí; LEON-RAMIREZ, Víctor and PEREZ-MALDONADO, Cruz Ishel. Role of hemodilution in postoperative infections in patients undergoing cardiac surgery. Rev. mex. anestesiol. [online]. 2022, vol.45, n.3, pp.172-177. Epub Sep 05, 2022. ISSN 0484-7903. https://doi.org/10.35366/105589.
Introduction:
The impact on the immune system of normovolemic hemodilution as a perioperative blood-saving technique raises a possible increase in immunoglobulin M, and a possible increase in infections, especially those associated with catheters.
Objective:
To compare the role of acute normovolemic hemodilution in postoperative infections in groups of patients undergoing cardiac surgery.
Material and methods:
A controlled clinical trial in 99 patients undergoing elective cardiac surgery who were randomized into two groups: group I (non-hemodiluted) and group II (hemodiluted). The presence or absence of infection was determined during the postoperative period. Data analysis was performed using descriptive and inferential statistics χ2. A p < 0.05 was considered significant. The data were processed using SPSS v.25.0.
Results:
The overall incidence of infection was 3.03%. Hemodiluted patients became infected more frequently than non-hemodiluted patients. The isolated organisms were Escherichia coli and Enterobacter aerogenes.
Conclusion:
Patients undergoing cardiac surgery who undergo acute normovolemic hemodilution suffer more frequently from postoperative infections than those who do not undergo acute normovolemic hemodilution.
Keywords : Cardiac surgery; hemodilution; infection.