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Revista de sanidad militar
Print version ISSN 0301-696X
Abstract
LANDEROS FLORES, Aldo; MORALES VASQUEZ, Iván and FRIAS AGUIRRE, Sintya Eloina. Effect on plasma glucose of the administration of dexamethasone in diabetic patients under balanced general anesthesia at the Hospital Central Militar. Rev. sanid. mil. [online]. 2018, vol.72, n.1, pp.10-14. Epub Aug 20, 2019. ISSN 0301-696X.
Background
Dexamethasone has an important role in the control of postoperative nausea and vomiting, since it has shown great efficacy; however, its use in diabetic patients is cautious or avoided by many anesthesiologists because of the increase in plasma glucose it produces.
Objective
To evaluate if there is a signifi cant increase in plasma glucose in diabetic patients after the administration of dexamethasone for prophylaxis of postoperative nausea and vomiting in balanced anesthesia.
Material and methods
Diabetic patients from the Hospital Central Militar undergoing surgery under balanced general anesthesia, divided into group 1 (dexamethasone) and group 2 (no dexamethasone). We measured baseline blood glucose, and two and 24 hours after the administration of dexamethasone or initiation of the anesthetic procedure; we applied a questionnaire on whether or not they had nausea, vomiting and pain assessment.
Results
Dexamethasone improved outcomes in postoperative pain, nausea and vomiting prevention; a greater increase in plasma glucose was observed in those who used dexamethasone, but in all of them, it was statistically non-signifi cant. Conclusion: We observed in the study that the use of dexamethasone increased plasma glucose in comparison with those patients in whom it was not used; however, it was not statistically signifi cant, and during the study, we observed no difference in the evolution of the patients that might suggest its use was harmful, so it can be recommended as an adjuvant for the prophylaxis of postoperative nausea and vomiting.
Keywords : Diabetes mellitus; postoperative nausea and vomiting.