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Ginecología y obstetricia de México

Print version ISSN 0300-9041

Abstract

RIVERA-CHAVEZ, Zaira; MORALES-HERNANDEZ, Fela Vanesa; GODINES-ENRIQUEZ, Myrna Souraye  and  LEON DOMINGUEZ, Jefsi Argelia. Prevalence of the causes of recurrent pregnancy loss in a third-level health care center. Ginecol. obstet. Méx. [online]. 2022, vol.90, n.7, pp.559-568.  Epub Sep 26, 2022. ISSN 0300-9041.  https://doi.org/10.24245/gom.v90i7.7658.

OBJECTIVE:

To determine the prevalence of the main etiological factors of recurrent gestational loss in the population of a tertiary care hospital.

MATERIALS AND METHODS:

Retrospective, cross-sectional, descriptive study carried out in patients with study protocol of two or more recurrent gestational losses who initiated prenatal control in the Obstetrics service or who were admitted to the Instituto Nacional de Perinatologia with a diagnosis of infertility between the months of January 2017 to January 2020. In each group, the etiological factors described in the international literature as possible causes of recurrent gestational loss were reviewed.

RESULTS:

280 patients were studied and the factor with the highest prevalence of recurrent gestational loss was endocrine with 56.78% (n = 159), followed by anatomic-uterine with 42.14% (n = 118) and thirdly infectious with 40.35% (n = 113). In the 75 patients in the infertility group, the most prevalent etiologic factor was endocrine (88%; n = 66), followed by anatomic-uterine (53.3%; n = 40) and then male (50.6%; n = 38). In patients in the obstetrics group, the factor with the highest prevalence was endocrine (45.36%; n = 93), followed by anatomic-uterine (38.04%; n = 78) and infectious (37%; n = 76).

CONCLUSIONS:

The factors related to recurrent gestational loss, described in the international literature and analyzed in this study, showed similar prevalences in institutional population. Those that differ are influenced by the characteristics of the population studied, the resources of the institution and, even, the diagnosis and service for which they were admitted as patients to the INPer.

Keywords : Recurrent pregnancy loss; Etiological factors; Diagnosis of infertility; Endocrine factor; Anatomic-uterine factor; Infectious factor.

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