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Ginecología y obstetricia de México

Print version ISSN 0300-9041

Abstract

AGUILAR-TORRES, Cesar Ramón et al. Linfoma de Burkitt en la mama durante el embarazo: reporte de un caso. Ginecol. obstet. Méx. [online]. 2021, vol.89, n.8, pp.647-654.  Epub Apr 04, 2022. ISSN 0300-9041.  https://doi.org/10.24245/gom.v89i8.4999.

BACKGROUND:

Burkitt 's lymphoma is derived from germ B cells; it is very aggressive and can have a high extranodal incidence, it is located even in sites as rare as the breast, it is associated with pregnancy and puerperium.

CLINICAL CASE:

19-year-old female patient, in the course of her second pregnancy, with childbirth two years prior to her current condition, irregular menstrual cycles, without contraceptive method. She sought care at a primary care center at 22 weeks of pregnancy due to enlargement of the right breast, which had begun 20 days earlier. Physical examination revealed: enlargement, erythema and hyperthermia in the right breast. Sonography reported: right breast with skin thickening, increased volume, heterogeneous echogenicity, increased and preserved vascularity, without adenopathies. In view of the insufficiency, hemodialysis was indicated, with satisfactory response. With the report of the biopsy and immunohistochemistry the diagnosis of Burkitt 's lymphoma was established. Chemotherapy with rituximab, etoposide, vincristine, doxorubicin and cyclophosphamide was indicated. Pregnancy was terminated at 34.4 weeks due to nonreassuring fetal status at the expense of nonreactive cardiotocographic recording (category 2) and type 1 intrauterine growth restriction.

CONCLUSION:

Breast masses produced by malignant neoplasms during pregnancy or puerperium represent a diagnostic challenge for the clinician. The diagnostic procedure and treatment should be performed by a multidisciplinary team.

Keywords : Burkitt 's lymphoma; B cells; Breast; Pregnancy; Physical examination; Hyperthermia; Sonography; Chemotherapy.

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