OBJECTIVE:

To describe a series of cases of multiple congenital arthrogryposes reported in fetal and newborn autopsies, performed in the pathology department of a high complexity hospital, between September 2016 and April 2019.

MATERIALS AND METHODS:

A retrospective descriptive study of a series of cases of autopsies, with anatomopathological findings of multiple congenital arthrogryposes, performed on fetuses and newborns, during the established time lapse.

RESULTS:

The analysis included 8 cases with an anatomopathological diagnose of multiple congenital arthrogryposes, six of them with PCR positive for ZIKA. Among the ultrasound reports, altered limb movement and abnormal central nervous system development (corpus callosum and cerebellum), were the main findings; which were confirmed by the anatomopathological study. Regarding perinatal results, 7/8 cases died during the first hour of life.

CONCLUSION:

In case of suspicion or confirmation of multiple congenital arthrogryposes by ultrasound, infectious processes should be ruled out; also, a clinical genetics consult should be sought to exclude associated alterations.

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