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Gaceta médica de México
On-line version ISSN 2696-1288Print version ISSN 0016-3813
Abstract
JIMENEZ-GONZALEZ, María del C.; MEJIA-AGUIRRE, Berenice and ASCENCIO-MONTIEL, Iván de J.. Microorganisms isolated in patients with post-cardiac surgery mediastinitis at a cardiology hospital of Mexico City. Gac. Méd. Méx [online]. 2023, vol.159, n.1, pp.17-23. Epub May 02, 2023. ISSN 2696-1288. https://doi.org/10.24875/gmm.22000163.
Introduction:
Mediastinitis after cardiovascular surgery gives rise to prolonged hospital stay and increased medical care costs, and is associated with high in-hospital mortality.
Objective:
To describe the clinical characteristics of patients with post-surgical mediastinitis, including the isolated microorganisms, resistance profile, and in-hospital survival.
Methods:
Cross-sectional study of patients with bacteriologically-confirmed post-surgical mediastinitis cared for at a cardiology hospital in Mexico City between January 2017 and March 2019.
Results:
Fifty-eight cases of mediastinitis were included. Median age was 67 years. Most subjects were males who underwent myocardial revascularization. During in-hospital follow-up, all-cause and mediastinitis-related mortality were 27.6% and 20.7%, respectively. Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli were the most commonly isolated microorganisms. High resistance to methicillin was found in coagulase-negative staphylococci, as well as high expression of extended-spectrum beta-lactamases in Escherichia coli and Klebsiella pneumoniae strains.
Conclusions:
High mortality and significant antimicrobial resistance were found in patients with post-cardiac surgery mediastinitis.
Keywords : Cardiac surgery; Mediastinitis; Microorganisms.