Resumen

VIDAL-MAYO, José de Jesús et al. Evaluation of the Status Epilepticus Severity Score (STESS) as a predictor of in-hospital mortality in patients with status epilepticus: a retrospective observational study. Arch. Neurocien. (Mex.) [online]. 2022, vol.27, n.4, pp.23-30.  Epub 23-Jun-2025. ISSN 2954-4122.  https://doi.org/10.31157/an.v27i4.374.

Status epilepticus (SE) is a medical emergency characterized by continuous or recurrent epileptic activity with high mortality. The Status Epilepticus Severity Score (STESS is a tool used to assess the prognosis of SE patients; however, However, its validity and appropriate cut-off points have not been established in Mexico. The objective of this study was to describe the clinical characteristics of patients with SE in our medical center, identify the variables associated with mortality, and evaluate the predictive capacity of the STESS scale for in-hospital mortality. Material and Methods: This was a retrospective cohort study that included sixty patients diagnosed with SE between 2000 and 2020. The STESS scale was applied to assess prognosis. Data on clinical characteristics and in-hospital mortality were collected. Cox regression analysis was conducted to determine the risk of mortality for each point on the scale, and the area under the ROC curve was calculated to determine its discriminatory capacity. Results: The majority of patients presented with generalized convulsive SE (51.7%), and the most common etiology was acute symptomatic SE (46.7%). The in-hospital mortality rate was 40%. The risk of mortality increased by 38% for each point on the STESS scale (B=0.38, HR=1.48, 95% CI: 1.13-1.94, p=0.005). The area under the ROC curve was 0.72, with an optimal cut-off point of ≥3 points for discriminating in-hospital mortality. Conclusions: The STESS scale showed a significant association with in-hospital mortality and can be used as a predictive tool for adverse outcomes in patients with SE.

Palabras llave : Status epilepticus; mortality; Status Epilepticus Severity Score.

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