Resumen

FERNANDO-JAMIOY, Diego et al. An unexpected connection: antiphospholipid syndrome and leprosy. A case report. Rev. mex. angiol. [online]. 2025, vol.53, n.2, pp.86-92.  Epub 14-Jul-2025. ISSN 2696-130X.  https://doi.org/10.24875/rma.24000036.

This clinical case addresses the rare coexistence of antiphospholipid syndrome (APS) and leprosy in a 43-year-old patient. The patient initially presented symptoms of dyspnea and precordial pain, leading to a diagnosis of pulmonary embolism and deep vein thrombosis. Throughout the treatment, the presence of antiphospholipid antibodies was discovered, specifically anticardiolipin and anti-β2-glycoprotein IgM, in addition to the diagnosis of leprosy confirmed by sural nerve biopsy. The report highlights the diagnostic and therapeutic complexity of this unusual association, emphasizing the need for an interdisciplinary approach and accurate diagnosis. The importance of more detailed research to fully understand the interaction between APS and leprosy, as well as its clinical implications and correlation with specific antibodies, is emphasized.

Palabras llave : Antiphospholipid syndrome (APS); Leprosy; Hansen’s disease.

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