Abstract

RAMOS-PENAFIEL, Christian O. et al. Novel coronavirus SARS-CoV-2 outbreak and cancer: A literature review. Gac. mex. oncol. [online]. 2022, vol.21, n.3, pp.110-115.  Epub Oct 03, 2022. ISSN 2565-005X.  https://doi.org/10.24875/j.gamo.22000179.

Cancer is a significant cause of death worldwide. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is spreading rapidly globally. Information on coronavirus disease 2019 (COVID-19) and its complications in cancer patients are still limited. It is relevant to consider that some chemotherapeutic agents have secondary immunosuppressive effects. Approximately 35% of hematologic cancer patients develop pneumonia caused by community respiratory viruses. People older than 65 years-old or with severe neutropenia or lymphopenia are at higher risk. Cancer patients with pneumonia infected by parainfluenza virus showed a higher risk of mortality compared to non-cancer patients (p < 0.05; 12.3% vs. 3.8%) or coronavirus infections (p < 0.01; 24% vs. 30%). Complications associated with SARS-COV2 infection in cancer patients are limited to descriptive studies, with those who received myeloablative, immunosuppressive or monoclonal antibody therapies being more susceptible.

Keywords : SARS-CoV-2; COVID-19; Cancer; Chemotherapy.

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