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Gaceta mexicana de oncología

On-line version ISSN 2565-005XPrint version ISSN 1665-9201


MANRIQUE-HINOJOSA, Javier et al. Human papillomavirus detection through the cobas® 4800 system in women from Lima, Peru. Gac. mex. oncol. [online]. 2021, vol.20, n.2, pp.46-51.  Epub Oct 18, 2021. ISSN 2565-005X.


Determine the prevalence of high-risk human papillomavirus (HR-HPV) infection in women from Lima between 2012 and 2013 using the cobas 4800 test


The study included 5324 women aged 30 or over, whose cervical samples underwent the cobas 4800 molecular test. Positive samples were analyzed through liquid-based cytology.


The prevalence of HR-HPV infection was 15.2%. Genotype 16 was found in 16.2%, genotype 18 in 3.1% and genotypes 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68 in 71.2%. 62.8% of samples were identified without cytological changes, 19.8% with LSIL, 14% with ASCUS, 2% with HSIL, and 0.7% with ASC-H.


The prevalence of HR-HPV in this study continues to be significant. In simple infections, the frequency of genotypes 16 and 18 stood out, and in coinfections, the group of the other twelve HPV-RA genotypes predominated.

Keywords : Papillomavirus Infections; Human papillomavirus DNA tests; Prevalence.

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