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Revista médica del Hospital General de México

versão On-line ISSN 2524-177Xversão impressa ISSN 0185-1063


SORDO-MEJIA, Ricardo et al. Anal tumors with infrequent histology: Analysis of a series of cases and literature review. Rev. med. Hosp. Gen. Méx. [online]. 2019, vol.82, n.3, pp.147-150.  Epub 06-Set-2021. ISSN 2524-177X.


The most frequent tumor of the anal region is epidermoid carcinoma; however, other types of tumors such as melanomas, sarcomas, and lymphomas can also develop. Most of them present similar symptoms although diagnosis and prognosis might be radically different.


The objective of this study was to report the clinical and histopathological characteristics of a group of patients diagnosed with non-epidermoid anal neoplasm in a third-level hospital.

Materials and Methods:

Eight patients with non-epidermoid anal neoplastic biopsy samples were evaluated from March 2013 to January 2017. Demographic data and histopathological results were obtained from the clinical records.


Mean age of the patients was 48.9 years (23-84); 37.5% of women and 62.5% of men. Patients presented with rectal bleeding in 25%, anal pain 87.5%, anal tumor 75%, and fever 25%. Among the patients, 37.5% presented with melanoma and 62.5% lymphoma. Regarding patients with lymphoma, 60% had plasmablastic lymphoma and 40% non-Hodgkin's lymphoma. The diagnostic time was 4 months on average (1-8 months) and 25% of the patients had been previously misdiagnosed with hemorrhoidal disease.


Non-epidermoid anal neoplasm cases are infrequent and its accurate diagnosis can take months, therefore, changing prognosis.

Palavras-chave : Melanoma; Plasmablastic lymphoma; Anal neoplasm abdominoperineal resection; Anal pain; Colonoscopy; Endoanal ultrasound.

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