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Revista alergia México

versión On-line ISSN 2448-9190


MORFIN-MACIEL, Blanca María  y  CASTILLO-MORFIN, Blanca María. Anaphylaxis caused by dermal exposure with cow’s milk in an adult with food allergy. A case report. Rev. alerg. Méx. [online]. 2020, vol.67, n.1, pp.73-78.  Epub 16-Sep-2020. ISSN 2448-9190.


Allergy to cow's milk proteins is the most frequent food allergy and its prevalence has increased in the last decade. Although most patients have symptoms after the intake of dairy milk, other routes of sensitization through skin and mucous membranes have been described.

Case report:

A 31-year-old male patient who is a professional chef and started with oropharyngeal symptoms after the intake of milk. Since he tolerated other dairy products, he did not suppress them from his diet. However, the clinical picture progressed and cutaneous symptoms were added; finally, anaphylaxis occurred by contact with bread dough that contained butter and milk. The patient was treated in the emergency department, where an increase in serum tryptase was verified. Skin prick tests and serological tests were positive for milk and its fractions.


Reports of anaphylaxis caused by dermal contact with cow’s milk are very scarce and they have been reported only in children. We believe that repeated food handling could favor cutaneous sensitization in adults with a personal history of atopy.

Palabras llave : Cow's milk allergy; Anaphylaxis; Adult; Skin sensitization; Tryptase.

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