Introduction:

central venous oxygen saturation (ScvO2) translates tissue oxygenation through the relationship between oxygen consumption and availability. Severe SARS-CoV-2 pneumonia impacts morbidity and mortality, so identifying patients at risk of disease progression through serum markers such as ScvO2 would be imperative.

Objective:

to identify whether ScvO2 is a prognostic marker in severe SARS-CoV-2 pneumonia.

Material and methods:

retrospective, longitudinal, descriptive, analytical study. The population was classified according to the value of ScvO2: Group 1: ScvO2 < 70%. Group 2: ScvO2 70-80%. Group 3: ScvO2 > 80%. The study variables were recorded, as well as the clinical outcome during their stay in the Intensive Care Unit (ICU): improvement or death.

Results:

115 patients were recruited, group 1 included 31 patients, group 2 and 3 included 52 and 32 patients respectively. Male sex was the most affected with 71 patients (61.7%). The median age was 65 years. Mortality was 51.6%, 42.3% and 68.8% for group 1, 2 and 3 respectively p ≥ 0.05. The ScvO2 group of 70-80% presented an inverse relationship with mortality with an exponent B -0.185, OR of 0.83 (95% CI 0.33-2.00) p = 0.69 while group 3 presented an exponent B of 1 with OR of 2.93 (95% CI 0.97-8.8) p = 0.05.

Conclusion:

ScvO2 > 80% in patients with severe SARS-CoV-2 pneumonia may be a prognostic factor for fatal outcome independent of PaO2/FiO2.

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