Abstract

ZARAGOZA-BASTIDA, Adrián et al. Cassia fistula extract as alternative treatment against gastrointestinal nematodes of sheep. Abanico vet [online]. 2019, vol.9, e92.  Epub Mar 05, 2021. ISSN 2448-6132.  https://doi.org/10.21929/abavet2019.92.

Gastrointestinal nematodes are an important issue in sheep production, these nematodes have developed resistance to traditional drugs, so it is necessary to search new functional and economic therapeutic alternatives; such as the use of plant extracts that have anthelmintic activity, Cassia fistula is a Leguminosae, due to its content of phenolic compounds, that can exhibit this activity, the aim of the present experiment was to determine the anthelmintic activity of hydroalcoholic extract from pods of Cassia fistula (LO) in vitro, using field nematodes in egg and larval stages to determine the inhibition percentage of eggs hatching and larval mortality. A hydroalcoholic extract of Cassia fistula pods was elaborated, stool samples of 20 sheep were collected, the feces were subjected to a parasitoscopic analysis to determine the presence of nematodes and eggs per gram of feces, they were used to obtain eggs and larvae, once obtained, they were challenged with LO (50, 25, 12.5 and 6.26 mg / mL) after the incubation time had elapsed, the percentages of eggs hatching inhibition and larval mortality close to 30% were determined. This suggests that LO has anthelmintic potential on gastrointestinal nematodes of sheep.

Keywords : Cassia fistula; gastrointestinal nematodes; antihelmintic activity.

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