SciELO - Scientific Electronic Library Online

vol.32 número4Albúmina sérica preoperatoria como un predictor de complicaciones posterior al reemplazo total de cadera en pacientes con artritis reumatoideEstudio comparativo entre Plate-Graff, Plate-Cage y Peek cage en la fusión de la columna cervical índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados




Links relacionados

  • No hay artículos similaresSimilares en SciELO


Acta ortopédica mexicana

versión impresa ISSN 2306-4102


CEJA-PICAZO, SU et al. Leucocyte esterase as a reliable diagnostic, cost-effective and fast in knee infections. Acta ortop. mex [online]. 2018, vol.32, n.4, pp.198-202.  Epub 04-Sep-2020. ISSN 2306-4102.


The articular infection represents a challenge due to its complexity and its devastating effect when not treated promptly. We have various diagnostic studies: cultures, ESR, CRP, count of leukocytes, among others but none is specific, it takes more than 30 minutes to complete and require complex infrastructure. In this study we determine the sensitivity and specificity of the leukocyte esterase for detection of an infectious process joint in Mexican population.

Material and methods:

From November 2015 to April 2016 was obtained synovial fluid from patients with diagnosis of knee infection with or without implant and without infection with degenerative pathology of the knee. It assessed the sample through the COMBI-SCREEN 11SYS leukocyte esterase with reading colorimetric test at two minutes determining positive for infection: two crosses, the remainder of the sample was sent to culture.


We perform the test in 64 samples of synovial fluid of knee joint 19 diagnosed with infection and 45 without infection. Was obtained a sensitivity 100%, specificity of 88.24%, PPV 68.42% and PNV 100%, kappa index 0.753 using the program IBM SPSS Statistics 22, Python ver. 2.7.


Leukocyte esterase is a fast, economical and effective to detect an infectious process against one inflammatory with high probability of success. This study showed an index of concordance 0.753 Kappa, proving to be reproducible so recommend be implemented in the emergency department at the national level.

Palabras llave : Septic arthritis; leukocyte esterase; knee; infection; replacement.

        · resumen en Español     · texto en Español     · Español ( pdf )