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Revista mexicana de neurociencia
versión On-line ISSN 2604-6180versión impresa ISSN 1665-5044
Resumen
PENA-DE LEON, Edilberto et al. Multidisciplinary consensus on the combined management of Alzheimers disease by Mexican experts: recommendations and guidelines. Rev. mex. neurocienc. [online]. 2024, vol.25, n.5, pp.138-142. Epub 14-Mar-2025. ISSN 2604-6180. https://doi.org/10.24875/rmn.24000023.
Objective:
Alzheimers disease (AD), affecting over 55 million people globally, poses a substantial public health challenge. Early diagnosis and appropriate treatment are vital to slowing its progression and enhancing patient quality of life. The fixed-dose combination of citicoline with rivastigmine emerges as a promising strategy AD treatment.
Methods:
A real-time Delphi consensus was reached with the participation of 11 Mexican experts.
Results:
The combination offers neuroprotective benefits, enhancing neuronal regeneration and reducing glutamate levels linked to neuronal damage in AD. These effects translate into improved cognitive function and delayed cognitive decline in AD.
Conclusions:
The Mexican Consensus for the Combined Management of AD endorses this fixed-dose combination of rivastigmine with citicoline as a new therapeutic perspective. Its efficacy and safety make it a valuable option for the treatment of this neurodegenerative disease.
Palabras llave : Alzheimers disease; Citicoline; Rivastigmine; Cholinesterase inhibitors; Fixed dose combination.
