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Revista mexicana de neurociencia

versión On-line ISSN 2604-6180versión impresa ISSN 1665-5044

Resumen

ALVARADO-GARCIA, Marco A. et al. Clinical characteristics in a cohort of patients with chronic inflammatory demyelinating polyneuropathy: a retrospective study. Rev. mex. neurocienc. [online]. 2024, vol.25, n.2, pp.29-34.  Epub 15-Oct-2024. ISSN 2604-6180.  https://doi.org/10.24875/rmn.23000055.

Objective:

The objective of the study is to evaluate the chronic inflammatory demyelinating polyneuropathy (CIDP) clinical spectrum in a cohort of Mexican patients who benefit from social security.

Methods:

A retrospective study of CIDP patients from 2010 to 2021. We documented neurological deficits, electrophysiological and laboratory parameters, diagnostic characteristics, disease activity, and clinical outcomes.

Results:

36 cases met the criteria of the EAN/PNS 2021, the mean age was 58.25 ± 10.10 years, 50% were women, and 69.4% used intravenous immunoglobulin (IVIG). Concerning functional status, 63.9% had an independent walk and 86.1% had mild weakness in manual skills. The analysis of functional status showed better results in the IVIG treatment group.

Conclusions:

Similar to previous literature reports, 50% of our patients had stable active disease. Considering the heterogeneity of the disease, more research about treatment initiation and long-term results is warranted.

Palabras llave : Chronic inflammatory demyelinating polyneuropathy; Polyneuropathy; Treatment; Functional status; Outcome characteristics.

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