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Boletín médico del Hospital Infantil de México

versión impresa ISSN 1665-1146


CASTELLANOS-MORFIN, Juana et al. Neonatal dengue. Case report. Bol. Med. Hosp. Infant. Mex. [online]. 2006, vol.63, n.3, pp.202-206. ISSN 1665-1146.

Introduction. There is little information about the effects of dengue infection upon the fetus, although the risk for this event increases during epidemic outbreaks. The vertical transmission of dengue is a rare event, a case is described below. Case report. The patient was a male, born after 40 weeks of gestation and on the 5th day of a maternal febrile illness. His Apgar score was 8/9, with weight, size and cephalic perimeter in the range of the 50 percentile. On the first 24 hours after the delivery the patient developed fever and antibiotics was given for neonatal sepsis. On the postpartum day 4 he showed irritability, intense crying and hypereflexia, meanwhile the laboratory revealed thrombocytopenia and leucopoenia. Neuroinfection was presumed and treatment with phototherapy and cefotaxime was begun (the lumbar puncture was avoided because thrombocytopenia and prolonged TPT). The blood culture was negative. IgM antibodies for dengue virus were positive in both, mother and neonate. On postpartum day 12, both, mother and child were discharged from the hospital, asymptomatic and with normal laboratory values. Conclusions. Usually, pregnant women with classic dengue have normal parturition and puerperium, as in this case. However, in the hemorrhagic dengue form there is an increased risk of delayed intrauterine growth, abortion, prematurity, premature rupture of membranes, preeclampsia and maternal or fetal death. The neonatal transmission of dengue is very rare, even in endemic countries with large epidemics; however it is an important condition that needs to be considered in the differential diagnosis of septic new-borns in endemic areas

Palabras llave : Neonatal dengue; vertical transmission.

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