SciELO - Scientific Electronic Library Online

vol.88 issue9Obesity and endometrial cancer: The impact of a public health problemImportance of surgical margins affected in cervical uterine conization author indexsubject indexsearch form
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • Have no similar articlesSimilars in SciELO


Ginecología y obstetricia de México

Print version ISSN 0300-9041


GUERRERO-VARGAS, José Juan  and  BARROS-DELGADILLO, Juan Carlos. Results in cycles of frozen-thawed embryo transfer: Analysis of two protocols of endometrial preparation. Ginecol. obstet. Méx. [online]. 2020, vol.88, n.9, pp.575-585.  Epub Oct 04, 2021. ISSN 0300-9041.


To compare the rate of live newborn with clinical pregnancy-embryo transfer, clinical characteristics and hormonal concentrations between two endometrial preparation schemes for devitrified embryo transfer: with a GnRH agonist (aGnRH) versus its replacement with high doses of estrogens.


Historical cohort observational study conducted in patients treated at the National Institute of Perinatology under IVF-ICSI protocol between January 2017-March 2019. Two endometrial preparation schemes were compared: group A with GnRH agonist and group B with estradiol at 8 mg per day without aGnRH. All patients had blood samples taken for FSH, LH, estradiol and progesterone determination and ultrasonographic follow-up during endometrial preparation.


in 99 patients between 23 and 42 years of age, with frozen embryos, the live birth-embryo transfer rate was 17.2 and 8.6%, (OR 1.98; CI95%: 077-1.53) and the clinical pregnancy rate was 26.5 and 22.8% (OR1.09; CI95%: 0.77-1.53) in groups a and b, respectively. total cycle length, estrogen days and serum estradiol concentration at the beginning of progesterone reached significant difference between groups. no clinical or laboratory data suggesting ovulation were detected.


The rate of live newborn was higher with GnRH agonists without reaching significance; however, endometrial preparation with estrogens alone is a safe, lower cost and more patient- and physician-friendLy scheme.

Keywords : Newborn; Pregnancy embryo transfer; GnRH agonists; Estradiol; Endometrium, estrogens, embryonic structures, embryo transfer; Frozen embryos; Pregnancy rate.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )