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Ginecología y obstetricia de México

versión impresa ISSN 0300-9041

Resumen

MEDINA-BUENO, Gonzalo Arturo. Prevalence of infection by genotypes of the PVH in women with ASCUS cytology. Ginecol. obstet. Méx. [online]. 2020, vol.88, n.7, pp.437-441.  Epub 24-Sep-2021. ISSN 0300-9041.  https://doi.org/10.24245/gom.v88i7.4167.

OBJECTIVE:

To estimate the prevalence of infection by genotypes of the human papilloma virus in women with squamous cell atypia of unknown significance (ASCUS).

MATERIALS AND METHOD:

Transversal and cross-sectional study of patients referred to the Carlos Alberto Seguín National Hospital, during 2018, for presenting ASCUS cytology, the Genoarray-Hybribio system for genotyping was reported. The study variables were: high-risk HPV genotypes, low-risk HPV, and age. Proportions and odds ratios were estimated with 95% confidence intervals.

RESULTS:

227 patients were studied, of which 95 had a positive test for HPV (41.8%). The prevalence for high-risk genotypes was 33.9%. The most frequent being 16, 31, 52 and 53. The prevalence was 4.8% for low-risk genotypes: 81, 6, 43, and 11, and 3.1% were mixed infections. 38 women had infection with less than two genotypes, women older than 30 years were 3 times more at risk of infection due to high-risk genotypes, Odss ratio 3.32 (95% CI 1.21-9.10) in relation to those younger than 30 years, statistical association significant p <0.01.

CONCLUSIONS:

The overall prevalence was 41.8%, the high-risk HPV infection in women with ASCUS was 33.9%, with the genotypes most prevalent in single infections being 16, 31, 52, and 53.

Palabras llave : Prevalence; Genotypes; Women; ASCUS; Mixed Infections; Papillomavirus Infection.

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