Abstract

WISNIAK, Jaime. Louis Alphonse Adrian. Educ. quím [online]. 2024, vol.35, n.1, pp.148-162.  Epub May 03, 2025. ISSN 0187-893X.  https://doi.org/10.22201/fq.18708404e.2024.1.81436.

Louis Alphonse Adrian (1832-1911) was a French pharmacist who with Auguste Trillat studied the synthesis and chemistry of phosphoglycerates, neutral and acid, their derivatives, properties, and dosage, particularly, organic and calcium phosphoglycerates, as well as the reaction between glycerin and phosphoric acid. They isolated several new first principles present in Artemisia absinthium, in Digitalis lutea, and in agaric acid. With Bardet and Blondel they carried a detailed botanical, chemical, and physiological study of Piligan, a moss originating from Brazil, and proved that the active component was the alkaloid piliganin. Adrian developed new dosage procedures for determining the amount of guaiacol present in commercial products.

Keywords : Absinthe; agaric acid; digitalis; guaiacol; phosphoglycerates; wormwood.

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