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vol.35 issue2Clinical and gasometric evolution in preterm newborns with volume ventilationAssociation of obstetric violence, prenatal control, and unplanned pregnancy with prematurity author indexsubject indexsearch form
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Perinatología y reproducción humana

On-line version ISSN 2524-1710Print version ISSN 0187-5337


YLLESCAS-MEDRANO, Eucario et al. VNFns vs. CPAPn as methods of extubation and rescue in newborns with respiratory distress. Perinatol. Reprod. Hum. [online]. 2021, vol.35, n.2, pp.57-64.  Epub May 06, 2022. ISSN 2524-1710.


Non-synchronized nasopharyngeal ventilation (VNFns) and continuous positive pressure of the nasal airway (CPAPn) are methods of non-invasive ventilatory support.


To compare the efficacy of the two methods as an extubation and rescue strategy.

Material and methods:

Patients who had been in one of both strategies from 2008 to 2012, categorizing them as extubation or rescue and measuring success or failure.


Success as an extubation strategy was 83.3% for VNFns against 68.7% for CPAPn (OR: 2.26). There was a difference for VNFns, in relation to hospitalization days, with a mean of 38.6 versus 65.4 days (p = 0.0001). Regarding bronchopulmonary dysplasia, there was a decreased risk (OR: 0.64; p = 0.01) for VNFns. There was a higher number of complications for CPAPn, columella injury, pneumomediastinum, pneumothorax and nasal bleeding. Hypocarbia was more frequent in VNFns.


VNFns was shown to be an effective and safe strategy, compared to CPAPn.

Keywords : Prematurity; CPAPn; VNFns; Extubation; Rescue; DBP.

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