SciELO - Scientific Electronic Library Online

vol.42 número2Evaluación de las necesidades de los cuidadores primarios informales de pacientes con trastorno límite de la personalidad: psicometría, caracterización y propuesta de intervención índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados




Links relacionados

  • No hay artículos similaresSimilares en SciELO


Salud mental

versión impresa ISSN 0185-3325


GALICIA-ALVARADO, Marlene et al. Cognitive and spectral coherence of EEG alterations in resting state in children with chronic TBI. Salud Ment [online]. 2019, vol.42, n.2, pp.91-100. ISSN 0185-3325.


TBI is associated with alterations in cortico-subcortical connectivity. However, little attention has been paid to its clinical characteristics and functional connectivity in pediatric patients with chronic TBI.


To evaluate the cognitive performance and spectral coherence of a group of children with TBI in non-acute phase.


Cross-sectional study of 15 children with chronic TBI and 17 healthy children. The Neuropsychological Assessment of Children (Evaluación Neuropsicológica Infantil, ENI) was used and the resting activity of the EEG with eyes-closed was recorded. Offline, two-second epochs of the EEG of each participant were chosen and the spectral coherence was estimated in a range of 1.6 to 30 Hz. The cognitive performance between groups was compared with T-test/Mann-Whitney U Test and MANOVA for the coherence values.


The TBI group showed a lower performance (p ≤ 0.05) in metalinguistic, visuospatial skills, attention, memory, non-verbal flexibility, planning, and organization. Differences (p ≤ 0.000) were found both inter and intrahemispherically in the spectral coherence between the groups, particularly on F1-F3 (95% CI: 0.543 - 0.557) over the whole frequency range and F3-C3 (95% CI: 0.503 - 0.515) in delta, theta, alpha2, and beta frequencies.

Discussion and conclusión

Our findings suggest alterations of hypo and hyper functional connectivity, particularly on the frontal and parietal lobes of both hemispheres, even after several years of a TBI. It is possible that a subtle difference in the degree of connectivity is crucial in the genesis or successful development of attentional, mnesic, executive, and visuospatial processes.

Palabras llave : EEG; cognition; child; traumatic brain injury.

        · resumen en Español     · texto en Inglés     · Inglés ( pdf )