SciELO - Scientific Electronic Library Online

 
vol.64 número2Riesgos de accidentes en el hogar: factores asociados y su efecto sobre la ocurrencia de accidentes en grupos vulnerablesEscudos sociales y balas mágicas para el control de la epidemia por Covid-19 en México índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

Links relacionados

  • No hay artículos similaresSimilares en SciELO

Compartir


Salud Pública de México

versión impresa ISSN 0036-3634

Resumen

PARRA-COLIN, Paola De La et al. Association of high-risk human papillomavirus with ocular surface squamous neoplasia: a case-control study in Mexico. Salud pública Méx [online]. 2022, vol.64, n.2, pp.209-217.  Epub 13-Mar-2023. ISSN 0036-3634.  https://doi.org/10.21149/12796.

Objective:

To investigate the association of high-risk human papilloma virus (HR-HPV) and other risk factors with ocular surface squamous cell neoplasia (OSSN).

Materials and methods:

We obtained DNA from 22 fresh frozen OSSN tissues and 22 pterygia as controls, we used a broad-spectrum HPV DNA amplification short PCR fragment to identify HPV infection in all specimens and then genotyped HPV by a reverse hybridization line probe assay. We also obtained demographic, sun exposure, and tobacco consumption information.

Results:

HR-HPV frequency was 40.9% in the OSSN group and 4.5% in the pterygia group (p=0.009). After covariate adjustment, OSSN was associated with HR-HPV (OR=16.3, 95%CI=1.2,218.1, p=0.03) and sunburn (OR=10.8, 95%CI=1.8,86.0, p=0.02).

Conclusions:

Ocular surface squamous cell neoplasia is a multifactorial disease. The strong association between HR-HPV and OSSN, suggests that HR-HPV could play an etiological role in OSSN development.

Palabras llave : squamous cell neoplasms; human papillomavirus; conjunctiva; pterygium; sunburn.

        · resumen en Español     · texto en Inglés