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Revista de investigación clínica

versão On-line ISSN 2564-8896versão impressa ISSN 0034-8376


GONZALEZ-DUARTE, Alejandra et al. II. The Research Ethics Involving Vulnerable Groups. Rev. invest. clín. [online]. 2019, vol.71, n.4, pp.217-225.  Epub 12-Abr-2021. ISSN 2564-8896.

Vulnerability in research occurs when the participant is incapable of protecting his or her interests and therefore, has an increased probability of being intentionally or unintentionally harmed. This manuscript aims to discuss the conditions that make a group vulnerable and the tools and requirements that can be used to reduce the ethical breaches when including them in research protocols. The vulnerability can be due either to an inability to understand and give informed consent or to unequal power relationships that hinder basic rights. Excluding subjects from research for the only reason of belonging to a vulnerable group is unethical and will bias the results of the investigation. To consider a subject or group as vulnerable depends on the context, and the investigator should evaluate each case individually.

Palavras-chave : Vulnerable groups; Women in research; Pregnant women; Low-income population; Low literacy; HIV and AIDS; Subordinates; Gender-diverse population; Informed consent; Research committee; Ethics committee; Institutional review board.

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