Resumo

SALAZAR-LEZAMA, Miguel Ángel. Historical considerations about of tuberculosis treatment. Neumol. cir. torax [online]. 2023, vol.82, n.4, pp.220-224.  Epub 07-Abr-2025. ISSN 2594-1526.  https://doi.org/10.35366/117938.

Although tuberculosis is as old as humanity, its medical treatment began in the 1940’s with the discovery of streptomycin. This discovery caused great expectation; However, shortly after it was noticed that patients who received it died just as well as those who did not. This gave way to treatment with multiple drugs due to the growth nature of M. Tuberculosis. Multiple treatments have been given since then, with various organizations worldwide participating. Due to the changing nature of the mycobacteria due to ineffective treatments or insufficient doses, the fight against this bacteria has been long, due to the appearance of monoresistance, polyresistance, evolving until today to the so-called extended resistance. All current research is aimed at better diagnostic tests and treatments that shorten its duration. This article reviews the history of medical treatment of tuberculosis.

Palavras-chave : tuberculosis; Mycobacterium tuberculosis; multidrug resistant; treatment.

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