Case description:

63-year-old male patient, with no history of direct family members with cancer, smoking rate of 50 packs/year, suspended three months prior to his evaluation due to dysphagia, without improvement, so he went to medical evaluation. A simple and contrast-enhanced chest tomography was performed, presenting a subcarinal mediastinal lesion measuring 58 × 51 × 74 mm and a mass in the apical segment of the right upper lobe, so it was decided to perform bronchoscopy to take a transcarinal biopsy. Which were performed using rigid tracheoscopy and flexible bronchoscopy, performing aspiration with a Wang needle, subsequently Forceps clamps and finally a flexible cryoprobe were introduced through the same puncture site with no evidence of hemorrhage after the procedures. Tissue measuring 0.6 × 0.3 × 0.2 cm was obtained through cryobiopsy, ideal for carrying out immunohistochemistry and mutation studies in pathology.