Abstract

SANCHEZ-ZAZUETA, Eduardo; MIYAGUI-ADAME, Kiyoshi Alejandro; GAMEZ-SAINZ, Ilse Lorenia  and  GALAVIZ-HUMO, Jesús. Primary extragonadal mixed germ cell tumor of the mediastinum. Case report. Neumol. cir. torax [online]. 2023, vol.82, n.1, pp.49-52.  Epub Oct 28, 2024. ISSN 0028-3746.  https://doi.org/10.35366/114231.

Germ cell tumors are usually neoplastic located in the testicles or ovaries manifested in early life. Extragonadal germ cell tumors are infrequent, representing 1 to 3% of extragonadal germ cell neoplasms. When they present, they are usually 1 to 2 excisions, the anterior mediastinum representing the most common site. They are usually asymptomatic in 20-40% of patients until there is compression or obstruction of nearby structures and there are no symptoms. We present the case of a 22 year old male without comorbidities who started with cough without hourly predominance, hemoptysis, fever, unintentional weight loss, diaphoresis, orthopnea, physical examination revealed pleuropulmonary condensation syndrome, cabinet studies were performed. initially chest X-ray confirmed by tomography chest, abdomen, pelvis, testicular ultrasound and serum studies a mass in the mediastinum located in the anterior compartment, a biopsy was taken and removal of the mediastinal mass, concluding in a primary extragonadal tumor of mixed germ cells of the mediastinum composed of three cell excisions, representing a diagnostic challenge due to their large size. were re offered treatment with chemotherapy based on bleomycin, etoposide, and cisplatin in four cycles without new relapses.

Keywords : mixed germ cell tumor; alpha-fetoprotein; mediastinum.

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