Abstract

CORRAL-VAZQUEZ, Rodolfo A. del; TAFOYA HERNANDEZ, Jesús Octavio  and  PARRA MACIAS, Agustín. Peritoneal Pseudomyxoma: A Case Report. Rev. Fac. Med. (Méx.) [online]. 2024, vol.67, n.3, pp.32-36.  Epub July 26, 2024. ISSN 2448-4865.  https://doi.org/10.22201/fm.24484865e.2024.67.3.04.

Pseudomyxoma peritonei (PMP) is a rare condition, first described by Werth in 1884 in association with ascites and ovarian mucinous tumors, and later in 1901 by Frankel, associated with appendicular mucinous tumors. High prevalence of mutations in the K-RAS and TP53 genes has been observed in patients with low-grade PMP, triggering proliferation and excessive mucus production. Studies have shown that the peritoneal cavity, especially the hepatic surface, is the main site for deposition of these tumors. Computed tomography is considered the gold standard for diagnosis, while magnetic resonance imaging is more sensitive for detecting the tumor origin and assessing disease extent. Although exploratory laparotomy is the traditional method for biopsy, less invasive alternatives such as ultrasound-guided and computed tomography-guided biopsy are being explored, which have proven to be effective. The differential diagnosis includes endometriosis and mixoid tumors, with emphasis on mesentery invasion and cystic characteristics. Recognizing differences in advanced stages is crucial, as PMP tends to invade organs from the outside, while mixoid tumors present distant solid metastases.

Keywords : Tumor; mucinous; mesentery; pseudomyxoma; peritoneum.

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