Abstract

CASTELLANOS, Manuel Ángeles  and  ESCOBAR, Carolina. From chronobiology to chronomedicine. Rev. Fac. Med. (Méx.) [online]. 2016, vol.59, n.2, pp.15-23. ISSN 2448-4865.

The major scientific advances in various biomedical areas as well as its demands for knowledge and dedication have moved away the researcher from of the patient’s bedside, and the clinician is gradually been transformed into a technician in medical care, leaving aside the scientific knowledge. Therefore the need to join the basic research and the clinic arose and to translate the findings of the laboratory to clinical medicine was born. The translational medicine appeared to give continuity to the evidence-based medicine obtained in the laboratory. However the basic biomedical research is not limited to metabolomics, proteomics, gene therapy or nanotechnology, just to mention a few research lines, some of these are much easier but are not less important. The study of biological rhythms is a clear example of successfully setting up the bridge between transmission and the application of basic science applied to health problems. The chronomedicine proposes a better understanding and manipulation of the physiology, using circadian variations as part of the diagnosis and treatment of certain pathologies.

Keywords : Circadian rhythm; suprachiasmatic nucleus; cancer; jet-lag; chronopharmacology.

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