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Gaceta médica de México

On-line version ISSN 2696-1288Print version ISSN 0016-3813

Abstract

BARRERA-LOPEZ, Francisco J.; NOYOLA-GARCIA, Maura E.; BARRERA-LOPEZ, Natalia G.  and  ALBARRAN-SANCHEZ, Alejandra. Surgical and medical complications associated with mucormycosis in a tertiary hospital. Gac. Méd. Méx [online]. 2025, vol.161, n.2, pp.154-160.  Epub June 20, 2025. ISSN 2696-1288.  https://doi.org/10.24875/gmm.24000366.

Background:

Mucormycosis is an infection caused by Mucorales. Management includes surgical treatment and antifungals.

Objective:

To describe the surgical and medical complications associated with mucormycosis in a third-level hospital.

Material and methods:

Records of patients with mucormycosis treated between 2019 and 2022 were collected.

Results:

A total of 25 patients were obtained, 17 (68%) men and 8 (32%) women. Surgical complications occurred on admission in 16% and early in 4% of cases. The most frequent medical complications were soft tissue infection on admission (84%) and late sepsis (52%). Amphotericin B deoxycholate was used in all cases, finding hypokalemia in 20 (80%), hypomagnesemia in 18 (72%), and acute kidney injury in 15 (60%).

Conclusions:

The most commonly performed surgery was surgical debridement on admission (76%). Surgical complications occurred mainly on admission (16%). The most frequent medical complications were soft tissue infection on admission (84 %) and late sepsis (52 %). Due to the high cost of the liposomal and lipid forms of amphotericin, the use of amphotericin B deoxycholate continues to persist in our setting, which leads to a high degree of renal toxicity and hydroelectrolytic alterations.

Keywords : Mucormycosis; Treatment; Complications.

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