Resumen

PRUTHVIRAJ, K.  y  SUNIL, K.. Synthesis and Characterization of tert-butyl 3-(((2-hydroxynaphthalen-1-yl)methylene)amino)-4-(4-(trifluoromethyl)phenyl)piperidine-1-carboxylate: A piperidine clubbed Boc protected versatile building block for multi functionalized chemical reactions. J. appl. res. technol [online]. 2025, vol.23, n.1, pp.103-107.  Epub 22-Ago-2025. ISSN 2448-6736.  https://doi.org/10.22201/icat.24486736e.2025.23.1.2611.

A novel fluorine containing a highly bioactive naturally abundant piperidine clubbed Schiff base derivative_tert-butyl_3-(((2-hydroxynaphthalen-1-yl)methylene)amino)-4-(4(trifluoromethyl) phenyl)piperidine-1- carboxylate (RSB1) a possible potent reactive building block was synthesized by condensing fluorine bearing piperidine containing boc protected amine derivative with the 2hydroxy naphthaldehyde using a simple condensation method in good yield and high purity. The structure characterization of the title compound was done by, 1H-NMR, 13C-NMR and HRMS spectral analysis.

Palabras llave : Schiff base; reactive building block; 2hydroxy naphthaldehyde; ¹H-NMR; ¹³C-NMR.

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