<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2448-8909</journal-id>
<journal-title><![CDATA[Medicina crítica (Colegio Mexicano de Medicina Crítica)]]></journal-title>
<abbrev-journal-title><![CDATA[Med. crít. (Col. Mex. Med. Crít.)]]></abbrev-journal-title>
<issn>2448-8909</issn>
<publisher>
<publisher-name><![CDATA[Colegio Mexicano de Medicina Crítica A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2448-89092023000400314</article-id>
<article-id pub-id-type="doi">10.35366/112165</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Saturación venosa central: ¿marcador pronóstico en neumonía grave por SARS-CoV-2?]]></article-title>
<article-title xml:lang="en"><![CDATA[Central venous oxygen saturation: prognostic marker in severe pneumonia due to SARS-CoV-2?]]></article-title>
<article-title xml:lang="pt"><![CDATA[Saturação venosa central: marcador prognóstico na pneumonia grave de SARS-CoV-2?]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez Pérez]]></surname>
<given-names><![CDATA[Natalia Itzel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Betancourt Vera]]></surname>
<given-names><![CDATA[Jesús Emmanuel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez Díaz]]></surname>
<given-names><![CDATA[Jesús Salvador]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Peniche Moguel]]></surname>
<given-names><![CDATA[Karla Gabriela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Buelna Gaxiola]]></surname>
<given-names><![CDATA[Fabiola]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Calyeca Sánchez]]></surname>
<given-names><![CDATA[María Verónica]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Mexicano del Seguro Social Centro Médico Nacional «Adolfo Ruiz Cortines» Hospital de Especialidades No. 14]]></institution>
<addr-line><![CDATA[Veracruz Veracruzm]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2023</year>
</pub-date>
<volume>37</volume>
<numero>4</numero>
<fpage>314</fpage>
<lpage>319</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2448-89092023000400314&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2448-89092023000400314&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2448-89092023000400314&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  Introducción:  la saturación venosa central de oxígeno (SvcO2) traduce oxigenación tisular a través de la relación entre el consumo y la disponibilidad de oxígeno. La neumonía grave por SARS-CoV-2 impacta en la morbimortalidad, por lo que identificar pacientes con riesgo de progresión de la enfermedad a través de marcadores séricos como la SvcO2 sería imperativo.  Objetivo:  identificar si la SvcO2 es un marcador pronóstico en la neumonía grave por SARS-CoV-2.  Material y métodos:  estudio retrospectivo, longitudinal, descriptivo, analítico. Se clasificó la población de acuerdo al valor de la SvcO2: Grupo 1: SvcO2 &lt; 70%. Grupo 2: SvcO2 70-80%. Grupo 3: SvcO2 &gt; 80%. Se registraron las variables de estudio así como el desenlace clínico durante su estancia en la unidad de cuidados intensivos (UCI): mejoría o defunción.  Resultados:  se reclutaron 115 pacientes, el grupo 1 incluyó 31 pacientes, el grupo 2 y 3 incluyeron 52 y 32 pacientes respectivamente. El sexo masculino fue el más afectado con 71 pacientes (61.7%). La media de edad fue de 65 años. La mortalidad fue de 51.6, 42.3 y 68.8% en el grupo 1, 2 y 3 respectivamente (p &#8805; 0.05). El grupo de SvcO2 de 70-80% presentó una relación inversa con mortalidad con un exponente B -0.185, OR de 0.83 (IC 95% 0.33-2.00) p = 0.69, mientras que el grupo 3 presentó un exponente B de 1 con OR de 2.93 (IC 95% 0.97-8.8) p = 0.05.  Conclusión:  la SvcO2 &gt; 80% en pacientes con neumonía grave por SARS-CoV-2 puede ser un factor de pronóstico para el desenlace fatal independiente de la PaO2/FiO2.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract:  Introduction:  central venous oxygen saturation (ScvO2) translates tissue oxygenation through the relationship between oxygen consumption and availability. Severe SARS-CoV-2 pneumonia impacts morbidity and mortality, so identifying patients at risk of disease progression through serum markers such as ScvO2 would be imperative.  Objective:  to identify whether ScvO2 is a prognostic marker in severe SARS-CoV-2 pneumonia.  Material and methods:  retrospective, longitudinal, descriptive, analytical study. The population was classified according to the value of ScvO2: Group 1: ScvO2 &lt; 70%. Group 2: ScvO2 70-80%. Group 3: ScvO2 &gt; 80%. The study variables were recorded, as well as the clinical outcome during their stay in the Intensive Care Unit (ICU): improvement or death.  Results:  115 patients were recruited, group 1 included 31 patients, group 2 and 3 included 52 and 32 patients respectively. Male sex was the most affected with 71 patients (61.7%). The median age was 65 years. Mortality was 51.6%, 42.3% and 68.8% for group 1, 2 and 3 respectively p &#8805; 0.05. The ScvO2 group of 70-80% presented an inverse relationship with mortality with an exponent B -0.185, OR of 0.83 (95% CI 0.33-2.00) p = 0.69 while group 3 presented an exponent B of 1 with OR of 2.93 (95% CI 0.97-8.8) p = 0.05.  Conclusion:  ScvO2 &gt; 80% in patients with severe SARS-CoV-2 pneumonia may be a prognostic factor for fatal outcome independent of PaO2/FiO2.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo:  Introdução:  a saturação venosa central de oxigênio (SvcO2) traduz a oxigenação tecidual por meio da relação entre consumo e disponibilidade de oxigênio. A pneumonia grave por SARS-CoV-2 afeta a morbidade e a mortalidade, portanto, seria imperativo identificar pacientes com risco de progressão da doença por meio de marcadores séricos, como SvcO2.  Objetivo:  identificar se a SvcO2 é um marcador prognóstico na pneumonia grave por SARS-CoV-2.  Material e métodos:  estudo retrospectivo, longitudinal, descritivo, analítico. A população foi classificada de acordo com o valor de SvcO2: grupo 1: SvcO2 &lt; 70%. Grupo 2: SvcO2 70-80%. Grupo 3: SvcO2 &gt; 80%. As variáveis do estudo foram registradas, assim como o desfecho clínico durante a internação na Unidade de Terapia Intensiva (UTI): melhora ou óbito.  Resultados:  foram recrutados 115 pacientes, o grupo 1 incluiu 31 pacientes, os grupos 2 e 3 incluíram 52 e 32 pacientes, respectivamente. O sexo masculino foi o mais acometido com 71 pacientes (61.7%). A média de idade foi de 65 anos. A mortalidade foi de 51.6%, 42.3% e 68.8% para os grupos 1, 2 e 3 respectivamente p &#8805; 0.05. O grupo SvcO2 de 70-80% apresentou relação inversa com mortalidade com expoente B -0.185 OR de 0.83 (IC 95% 0.33-2.00) p = 0.69 enquanto o grupo 3 apresentou expoente B de 1 com OR de 2.93 (IC 95% 0.97-8.8) p = 0.05.  Conclusão:  SvcO2 &gt; 80% em pacientes com pneumonia grave por SARS-CoV-2 pode ser um fator prognóstico para desfecho fatal independente de PaO2/FiO2.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[saturación venosa central de oxígeno]]></kwd>
<kwd lng="es"><![CDATA[neumonía grave]]></kwd>
<kwd lng="es"><![CDATA[SARS-CoV-2]]></kwd>
<kwd lng="en"><![CDATA[central venous oxygen saturation]]></kwd>
<kwd lng="en"><![CDATA[severe pneumonia]]></kwd>
<kwd lng="en"><![CDATA[SARS-CoV-2]]></kwd>
<kwd lng="pt"><![CDATA[saturação venosa central de oxigênio]]></kwd>
<kwd lng="pt"><![CDATA[pneumonia grave]]></kwd>
<kwd lng="pt"><![CDATA[SARS-CoV-2]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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