<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2448-6132</journal-id>
<journal-title><![CDATA[Abanico veterinario]]></journal-title>
<abbrev-journal-title><![CDATA[Abanico vet]]></abbrev-journal-title>
<issn>2448-6132</issn>
<publisher>
<publisher-name><![CDATA[Sergio Martínez González]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2448-61322021000100109</article-id>
<article-id pub-id-type="doi">10.21929/abavet2021.15</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Efecto del closantel combinado con fenbendazol sobre huevos de parásitos gastrointestinales en caballos]]></article-title>
<article-title xml:lang="en"><![CDATA[Effect of closantel combined with fenbendazole on the eggs of gastrointestinal parasites in horses]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Cerna-Adame]]></surname>
<given-names><![CDATA[Roberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Barrón-Bravo]]></surname>
<given-names><![CDATA[Oscar]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Angel-Sahagún]]></surname>
<given-names><![CDATA[Cesar]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hernández-Marín]]></surname>
<given-names><![CDATA[Antonio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Arredondo-Castro]]></surname>
<given-names><![CDATA[Mauricio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Avila-Ramos]]></surname>
<given-names><![CDATA[Fidel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Guanajuato  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Instituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias  ]]></institution>
<addr-line><![CDATA[ Tamaulipas]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2021</year>
</pub-date>
<volume>11</volume>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2448-61322021000100109&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2448-61322021000100109&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2448-61322021000100109&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN: Los parásitos gastrointestinales deben controlarse periódicamente en los caballos para mantener su rendimiento productivo y adecuado estado de salud. El objetivo de la investigación fue conocer el efecto e inocuidad del closantel combinado con fenbendazol sobre huevos de parásitos gastrointestinales en equinos. La combinación del fármaco se administró a 102 caballos de diferente raza, edad, sexo y peso corporal a dosis de 10 mg por kg cada fármaco. Las constantes fisiológicas se midieron antes y 90 minutos después de administrado el gel. Adicionalmente, se colectó una muestra de heces directamente al recto de los caballos durante la exploración física para determinar la presencia y cantidad de huevos. En animales positivos se tomaron muestras a los 15, 30 y 45 días posteriores al tratamiento para conocer el tiempo que pueden proteger a los caballos los fármacos administrados. En los resultados 53 caballos fueron positivos a parásitos, el fármaco presentó eficacia del 99% a los 15 días post tratamiento y del 89.79% a los 45 días, en los 102 caballos que recibieron el tratamiento no presentaron ningún efecto sobre las variables fisiológicas evaluadas. Se concluye que la combinación de closantel con fenbendazol a 10 mg por kg de peso corporal tiene eficacia del 99% post aplicación y no causo efecto negativo para los caballos independientemente del sexo y la edad.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT Gastrointestinal parasites should be periodical controlled in horses to maintain their productive performance and adequate health. The objective of the research was to know the effect and safety of closantel combined with fenbendazole on the eggs of gastrointestinal parasites in horses. The drug combination was administered to 102 horses of different breed, age, sex and body weight at a dose of 10 mg per kg each drug. Physiological constants were measured before and 90 minutes after the drug was administered. Additionally, a sample was collected directly from the rectum of the horses during the physical examination to determine the presence and quantity of eggs. In positive animals, samples were taken 15, 30 y 45 days after treatment to determine the time that the administrated drugs can protect the horses. In the results, 53 horses were positive for parasites, the drug showed efficacy of 99% at 15 days after treatment and 89.79 at 45 days, in the 102 treated horses there was no effect on the physiological variables evaluated. It is concluded that the combination of closantel with fenbendazole at 10 mg per kg of body weight has efficacy of 99% post application and is safe for horses.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Equinos]]></kwd>
<kwd lng="es"><![CDATA[antihelmínticos]]></kwd>
<kwd lng="es"><![CDATA[endectocidas]]></kwd>
<kwd lng="es"><![CDATA[reacción adversa]]></kwd>
<kwd lng="es"><![CDATA[huevos gastrointestinales]]></kwd>
<kwd lng="es"><![CDATA[inocuidad]]></kwd>
<kwd lng="en"><![CDATA[Anthelmintics]]></kwd>
<kwd lng="en"><![CDATA[endectocides]]></kwd>
<kwd lng="en"><![CDATA[adverse reaction]]></kwd>
<kwd lng="en"><![CDATA[gastrointestinal eggs]]></kwd>
<kwd lng="en"><![CDATA[innocuous]]></kwd>
</kwd-group>
</article-meta>
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