<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1870-199X</journal-id>
<journal-title><![CDATA[Revista odontológica mexicana]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Odont. Mex]]></abbrev-journal-title>
<issn>1870-199X</issn>
<publisher>
<publisher-name><![CDATA[Universidad Nacional Autónoma de México, Facultad de Odontología]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1870-199X2015000300155</article-id>
<article-id pub-id-type="doi">10.1016/j.rodmex.2015.07.002</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Tratamiento periodontal no quirúrgico en pacientes con gingivitis y periodontitis moderada. Respuesta bioquímica y microbiológica]]></article-title>
<article-title xml:lang="en"><![CDATA[Non surgical periodontal treatment in patients with gingivitis and moderate periodontitis. Biochemical and microbiological response]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Macín-Cabrera]]></surname>
<given-names><![CDATA[Susana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="A a"/>
<xref ref-type="aff" rid="A02"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sanz-Alonso]]></surname>
<given-names><![CDATA[Mariano]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Castrillón-Rivera]]></surname>
<given-names><![CDATA[Laura]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Palma-Ramos]]></surname>
<given-names><![CDATA[Alejandro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Noguez-Méndez]]></surname>
<given-names><![CDATA[Norma]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Quirino-Barreda]]></surname>
<given-names><![CDATA[Carlos]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rubio-Martínez]]></surname>
<given-names><![CDATA[Alejandro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="A01">
<institution><![CDATA[,Universidad Autónoma Metropolitana Unidad Xochimilco Departamento de Atención a la Salud]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="A02">
<institution><![CDATA[,Universidad Complutense de Madrid Facultad de Odontología ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Spain</country>
</aff>
<aff id="A03">
<institution><![CDATA[,Universidad Autónoma Metropolitana Unidad Xochimilco Departamento de Sistemas Biológicos]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="A04">
<institution><![CDATA[,Universidad Autónoma Metropolitana Unidad Xochimilco Departamento de Sistemas Biológicos]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="A05">
<institution><![CDATA[,Instituto Tecnológico de Querétaro Departamento de Química Laboratorio de Polímeros]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2015</year>
</pub-date>
<volume>19</volume>
<numero>3</numero>
<fpage>155</fpage>
<lpage>164</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S1870-199X2015000300155&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S1870-199X2015000300155&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S1870-199X2015000300155&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[ Objetivo: Conocer la respuesta inflamatoria a través de la presencia de interleucina 1&#946; e identificar microorganismos patógenos como posibles marcadores inmunológicos y microbiológicos en el diagnóstico y tratamiento periodontal no quirúrgico en sujetos con gingivitis y periodontitis crónica moderada en población mexicana.  Material y métodos: En este estudio prospectivo de cohortes, se seleccionaron 18 pacientes con signos clínicos de gingivitis y 17 pacientes con periodontitis crónica moderada, se recolectaron las muestras de biopelícula subgingival y de fluido gingival crevicular. Se cuantificó la interleucina 1&#946; durante las fases pretratamiento, postratamiento y de mantenimiento del tratamiento periodontal no quirúrgico.  Resultados: Las variables de respuesta microbiológica mostraron que Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, Aggregatibacter actinomycetemcomitans disminuyeron significativamente en individuos con gingivitis. Así como Porphyromonas gingivalis, Tannerella forsythia, Fusobacterium nucleatum, Aggregatibacter actinomycetemcomitans y Actinomyces sp. en periodontitis crónica moderada. Las variables de respuesta bioquímica mostraron una disminución significativa en la concentración y cuenta total de interleucina 1&#946; en los individuos con periodontitis crónica moderada en la fase de mantenimiento del tratamiento así como de las variables de respuesta clínica.  Conclusión: Hay reducción de los niveles de interleucina 1&#946; con la disminución de la microflora. Los niveles de interleucina 1&#946; son marcadores sensibles para el diagnóstico y severidad de la enfermedad periodontal.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ Objective: To ascertain inflammatory response through interleucina 1&#946; presence and identify pathogenic microorganisms as possible immunological and microbiological markers in diagnosis and treatment non-surgical periodontal in patients with gingivitis and moderate chronic periodontitis in a sample of Mexican population.  Material and methods: In the present prospective cohort study, 18 patients with signs of gingivitis and 17 patients with moderate chronic periodontitis were selected. Samples of subgingival biofilm and of crevicular gingival fluid were collected. Interleukine 1&#946; was quantified during the pre-treatment, post-treatment and maintenance phases of the nonsurgical periodontal treatment. Continuous variables were analyzed with the Student test, as well as categorical variables which were analyzed with the TurkeyKramer test. For independent groups the Pearson test was used.  Results: Microbiological response variables showed that Porphyromonas gingivalis, Prevotella intermedia , Fusobacterium nucleatum , Aggregatibacter actinomycetemcomitans significantly decreased in subjects with gingivitis. Porphyromonas gingivalis , Tannerella forsythia , Fusobacterium nucleatum , Aggregatibacter actinomycetemcomitans and Actinomyces ssp . decreased in cases. Biochemical response variables showed significant decrease in IL-1&#946; concentration and total count in individuals with moderate chronic periodontitis in treatment maintenance phase. The same result applied to clinical response variables.  Conclusions: There is a decrease in Interleukin 1&#946; levels with decrease in microflora. Interleukin 1&#946; are sensitive markers for diagnosis of periodontal disease and assessment of its severity.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Tratamiento periodontal no quirúrgico]]></kwd>
<kwd lng="es"><![CDATA[población mexicana]]></kwd>
<kwd lng="es"><![CDATA[gingivitis]]></kwd>
<kwd lng="es"><![CDATA[periodontitis crónica moderada]]></kwd>
<kwd lng="en"><![CDATA[Non surgical periodontal treatment]]></kwd>
<kwd lng="en"><![CDATA[Mexican population]]></kwd>
<kwd lng="en"><![CDATA[gingivitis]]></kwd>
<kwd lng="en"><![CDATA[moderate periodontitis]]></kwd>
</kwd-group>
</article-meta>
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<article-title xml:lang=""><![CDATA[Interleukin-1 beta, interleukin-12 and interleukin -18 levels in gingival fluid serum of patients with gingivitis and periodontitis]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Orozco]]></surname>
<given-names><![CDATA[A.]]></given-names>
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<name>
<surname><![CDATA[Gemmell]]></surname>
<given-names><![CDATA[E.]]></given-names>
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<surname><![CDATA[Bickel]]></surname>
<given-names><![CDATA[M.]]></given-names>
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<given-names><![CDATA[G.J.]]></given-names>
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<source><![CDATA[Oral Microbiol Immunol.]]></source>
<year>2006</year>
<volume>21</volume>
<page-range>256-60</page-range></nlm-citation>
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