<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0484-7903</journal-id>
<journal-title><![CDATA[Revista mexicana de anestesiología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. mex. anestesiol.]]></abbrev-journal-title>
<issn>0484-7903</issn>
<publisher>
<publisher-name><![CDATA[Colegio Mexicano de Anestesiología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0484-79032022000200101</article-id>
<article-id pub-id-type="doi">10.35366/103884</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Evaluación de las características de la prescripción de opioides mayores otorgados por las farmacias de un Hospital General Latinoamericano]]></article-title>
<article-title xml:lang="en"><![CDATA[Evaluation of the prescription characteristics of major opioids dispensed by the pharmacies of a Latin American General Hospital]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Covarrubias-Gómez]]></surname>
<given-names><![CDATA[Alfredo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Zavaleta-Monestel]]></surname>
<given-names><![CDATA[Esteban]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Villalobos-Madríz]]></surname>
<given-names><![CDATA[Jorge Arturo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez-Miranda]]></surname>
<given-names><![CDATA[Roberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Díaz-Madríz]]></surname>
<given-names><![CDATA[José Pablo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Serrano-Arias]]></surname>
<given-names><![CDATA[Bruno]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Meoño-Elizondo]]></surname>
<given-names><![CDATA[Adriana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Zheng-Mok]]></surname>
<given-names><![CDATA[Wai Yee]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán Centro Algia para la Educación en Salud Departamento de Medicina del Dolor y Paliativa]]></institution>
<addr-line><![CDATA[ Ciudad de México]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Clínica Bíblica Departamento de Farmacia ]]></institution>
<addr-line><![CDATA[San José ]]></addr-line>
<country>Costa Rica</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad de Ciencias Médicas Departamento de Farmacia ]]></institution>
<addr-line><![CDATA[San José ]]></addr-line>
<country>Costa Rica</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Hospital Clínica Bíblica Departamento de Anestesiología ]]></institution>
<addr-line><![CDATA[San José ]]></addr-line>
<country>Costa Rica</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Hospital Clínica Bíblica Departamento de Farmacia ]]></institution>
<addr-line><![CDATA[San José ]]></addr-line>
<country>Costa Rica</country>
</aff>
<aff id="Af6">
<institution><![CDATA[,Universidad de Ciencias Médicas Departamento de Farmacología ]]></institution>
<addr-line><![CDATA[San José ]]></addr-line>
<country>Costa Rica</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2022</year>
</pub-date>
<volume>45</volume>
<numero>2</numero>
<fpage>101</fpage>
<lpage>106</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0484-79032022000200101&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0484-79032022000200101&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0484-79032022000200101&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  Introducción:  Los opioides se han utilizado para el alivio del dolor en diversos contextos. Su uso puede favorecer efectos indeseables. Actualmente los países industrializados viven una crisis de opioides.  Objetivos:  Caracterizar los opioides mayores despachados en términos de especialidad médica y de dosis total en miligramos equivalentes a morfina (MME) en un Hospital General Latinoamericano.  Material y métodos:  Se realizó un estudio retrospectivo y observacional de prescripciones de opioides mayores despachadas en las Farmacias de un Hospital General Latinoamericano entre el año 2017 y 2020. Se tomó información de la base de datos del Ministerio de Salud. Se excluyeron las recetas que contenían estupefacientes no opioides y fentanilo inyectable. Se realizó una estandarización a MME para analizar la distribución de la prescripción según médicos y pacientes.  Resultados:  La cantidad total de recetas despachadas correspondientes a opioides mayores fue de 5,366 prescripciones. La morfina inyectable fue el medicamento más prescrito (46%) y como principio activo obtuvo 54% de todas las recetas estudiadas (considerando todas las vías de administración). Medicina general prescribió la mayoría de las recetas con un 48%, lo que representó 42% del total de MME.  Conclusiones:  La morfina es el principio activo preferido por los médicos evaluados en este estudio, la vía de administración parenteral es la más utilizada. Medicina general es el área que más prescribe opioides. Es pertinente crear políticas educativas en materia de opioides; por ello, resulta conveniente caracterizar la prescripción de manera cualitativa considerando información como el diagnóstico y las dosis diarias utilizadas.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract:  Introduction:  Opioids have been used for pain relief in various settings. Its use can promote undesirable effects. Industrialized countries are currently experiencing an opioid crisis.  Objective:  To characterize the prescription of major opioids considering the medical area that made the prescription and total dose in milligrams morphine equivalents (MME) at a general hospital in Latin America.  Material and methods:  A retrospective and observational study was carried out. The number of prescriptions for major opioids dispensed in the pharmacies of a general hospital in Latin America, between 2017 and 2020, were documented. Information was taken from the database of the Ministry of Health. Prescriptions containing non-opioid narcotic drugs and injectable Fentanyl were excluded. A standardization to MME was carried out to analyze the distribution of prescriptions.  Results:  The total number of prescriptions filled for major opioids was 5,366 prescriptions. Injectable morphine was the most prescribed drug (46%) and as an active principle it obtained 54% of all the prescriptions studied (considering all routes of administration). General medicine prescribed most prescriptions (48%), which represented 42% of the total MME.  Conclusions:  Morphine is the substance preferred by the doctors evaluated in this study, the parenteral route of administration is the most used. General medicine is the area that prescribes most of the opioids. It is pertinent to create educational policies on opioids; therefore, it is convenient to characterize the prescription qualitatively considering information such as the diagnosis and the daily doses used.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Analgésicos]]></kwd>
<kwd lng="es"><![CDATA[opioides]]></kwd>
<kwd lng="es"><![CDATA[prescripción]]></kwd>
<kwd lng="es"><![CDATA[hospital]]></kwd>
<kwd lng="es"><![CDATA[medicina]]></kwd>
<kwd lng="en"><![CDATA[Painkillers]]></kwd>
<kwd lng="en"><![CDATA[opioids]]></kwd>
<kwd lng="en"><![CDATA[prescription]]></kwd>
<kwd lng="en"><![CDATA[hospital]]></kwd>
<kwd lng="en"><![CDATA[medicine]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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