<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0484-7903</journal-id>
<journal-title><![CDATA[Revista mexicana de anestesiología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. mex. anestesiol.]]></abbrev-journal-title>
<issn>0484-7903</issn>
<publisher>
<publisher-name><![CDATA[Colegio Mexicano de Anestesiología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0484-79032022000200087</article-id>
<article-id pub-id-type="doi">10.35366/103882</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Ensayo clínico: efecto del sulfato de magnesio sobre los niveles séricos de lactato en el seno coronario]]></article-title>
<article-title xml:lang="en"><![CDATA[Clinical trial: effect of magnesium sulfate on serum levels of lactate in the coronary sinus]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Santiago-López]]></surname>
<given-names><![CDATA[Janaí]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[León-Ramírez]]></surname>
<given-names><![CDATA[Víctor]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gutiérrez-Sánchez]]></surname>
<given-names><![CDATA[David Guillermo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Mexicano del Seguro Social Centro Médico Nacional «Siglo XXI» Hospital de Cardiología]]></institution>
<addr-line><![CDATA[ Ciudad de México]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Instituto Mexicano del Seguro Social Centro Médico Nacional «Siglo XXI» Hospital de Cardiología]]></institution>
<addr-line><![CDATA[ Ciudad de México]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Instituto Mexicano del Seguro Social Centro Médico Nacional «Siglo XXI» Hospital de Cardiología]]></institution>
<addr-line><![CDATA[ Ciudad de México]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2022</year>
</pub-date>
<volume>45</volume>
<numero>2</numero>
<fpage>87</fpage>
<lpage>91</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0484-79032022000200087&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0484-79032022000200087&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0484-79032022000200087&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  Introducción:  Se han propuesto varios métodos para controlar la inflamación y preservar el miocardio durante la circulación extracorpórea (CEC), entre ellos podemos mencionar la administración de electrolitos, tales como el magnesio (Mg2+).  Objetivo:  Comparar el efecto del uso de sulfato de magnesio (MgSO4) prepinzamiento aórtico (pre-PAo) vs placebo sobre los niveles séricos de lactato en el seno coronario en pacientes sometidos a revascularización miocárdica (RVM) multivaso con CEC.  Material y métodos:  Se realizó un ensayo clínico controlado en 52 pacientes sometidos a RVM multivaso con CEC, aleatorizados para recibir placebo (grupo I) o MgSO4 (grupo II) pre-PAo, y se tomaron muestras sanguíneas del seno coronario en dos tiempos diferentes: T0: pre-PAo y T1: previo al cierre de tórax, cuantificándose el lactato sérico. Para su análisis, se utilizó t de Student y &#967;2. Una p &lt; 0.05 fue significativa. La información se procesó en SPSS v-22.0.  Resultados:  Los niveles séricos de lactato en el seno coronario postpinzamiento aórtico (pos-PAo) fueron menores en el grupo II (2.967 ± 0.86 vs 2.154 ± 1.14) mostrando diferencias significativas (p = 0.006).  Conclusión:  El uso de MgSO4 pre-PAo disminuye los niveles séricos de lactato en el seno coronario en pacientes sometidos a RVM multivaso con CEC.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract:  Introduction:  Several methods have been proposed to control inflammation and to preserve the myocardium during cardiopulmonary bypass (CABG), including the administration of electrolytes such as magnesium (Mg2+).  Objective:  To compare the effect of using magnesium sulfate (MgSO4) or a placebo before aortic clamping (AoC) on the serum levels of lactate in the coronary sinus in patients undergoing myocardial multivessel revascularization (MRV) with CABG.  Material and methods:  A clinical assay was conducted with 52 patients undergoing MRV multivessel with CEC; the patients were randomized to receive a placebo (group I) or MgSO4 (group II) before AoC, and blood samples were taken from the coronary sinus to quantify serum lactate at two different times: T0: pre-AoC and T1: before closing the chest. Statistical analysis was performed on Student&#8217;s t-test and &#967;2. A p &lt; 0.05 was considered statistically significant. The data were processed with SPSS v-22.0.  Results:  Serum levels of lactate in the coronary sinus post-AoC were lower in group II (2.967 ± 0.86 vs 2.154 ± 1.14), with significant differences (p = 0.006).  Conclusion:  The use of MgSO4 before AoC reduces serum lactate levels in the coronary sinus in patients undergoing MRV multivessel with CABG.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Magnesio]]></kwd>
<kwd lng="es"><![CDATA[lactato sérico]]></kwd>
<kwd lng="es"><![CDATA[seno coronario]]></kwd>
<kwd lng="es"><![CDATA[cirugía cardíaca]]></kwd>
<kwd lng="es"><![CDATA[revascularización miocárdica]]></kwd>
<kwd lng="en"><![CDATA[Magnesium]]></kwd>
<kwd lng="en"><![CDATA[serum lactate]]></kwd>
<kwd lng="en"><![CDATA[coronary sinus]]></kwd>
<kwd lng="en"><![CDATA[heart surgery]]></kwd>
<kwd lng="en"><![CDATA[myocardial revascularization]]></kwd>
</kwd-group>
</article-meta>
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