<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0300-9041</journal-id>
<journal-title><![CDATA[Ginecología y obstetricia de México]]></journal-title>
<abbrev-journal-title><![CDATA[Ginecol. obstet. Méx.]]></abbrev-journal-title>
<issn>0300-9041</issn>
<publisher>
<publisher-name><![CDATA[Federación Mexicana de Colegios de Obstetricia y Ginecología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0300-90412019000900610</article-id>
<article-id pub-id-type="doi">10.24245/gom.v87i9.3126</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Sarcoma de Ewing como causa de sangrado uterino anormal. Reporte de un caso]]></article-title>
<article-title xml:lang="en"><![CDATA[Ewing&amp;apos;s sarcoma as a cause of abnormal uterine bleeding. Report of a case]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Villalobos-Equihua]]></surname>
<given-names><![CDATA[Carolina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ruiz-Marines]]></surname>
<given-names><![CDATA[Daniel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ortíz-Verdín]]></surname>
<given-names><![CDATA[Maira Denisy]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Martínez-Hernández]]></surname>
<given-names><![CDATA[Francisco Javier]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital de la Mujer de Morelia  ]]></institution>
<addr-line><![CDATA[ Michoacán]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital de la Mujer de Morelia  ]]></institution>
<addr-line><![CDATA[ Michoacán]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital de la Mujer de Morelia  ]]></institution>
<addr-line><![CDATA[ Michoacán]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Hospital de la Mujer de Morelia  ]]></institution>
<addr-line><![CDATA[ Michoacán]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2019</year>
</pub-date>
<volume>87</volume>
<numero>9</numero>
<fpage>610</fpage>
<lpage>614</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0300-90412019000900610&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0300-90412019000900610&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0300-90412019000900610&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  ANTECEDENTES: Los tumores neuroectodérmicos primitivos se originan de células progenitoras mesenquimales y forman parte de diversas neoplasias: familia de tumores de Ewing. Su expresión en el aparato reproductor femenino (principalmente en el ovario y el cuerpo uterino) es un suceso excepcional.  CASO CLÍNICO: Paciente de 13 años, que acudió al servicio de urgencias ginecológicas del Hospital de la Mujer de Morelia, Michoacán, con hipermenorrea de 5 meses de evolución, dolor tipo cólico en el hipogastrio, sin mejoría a pesar del consumo de analgésicos; pérdida de 3 kg en 1 mes y afectación al estado general de salud. A la exploración física se encontró: abdomen con tumoración de 10 x 10 cm en el hueco pélvico. Se decidió efectuar laparotomía exploradora con histerectomía total abdominal, ooferectomía derecha y salpingectomía izquierda. El estudio anatomopatológico reportó un tumor de células pequeñas redondas y azules, que afectaba el fondo del saco vaginal y el cérvix. El estudio de inmunohistoquímica confirmó el diagnóstico de sarcoma de Ewing. La paciente fue enviada al centro estatal de Oncología para recibir quimioterapia y radioterapia; sin embargo, se perdió en el seguimiento.  CONCLUSIONES: El sangrado uterino anormal es uno de los motivos más frecuentes de consulta ginecológica en adolescentes, que asociado con alguna neoplasia resulta un suceso excepcional. Los sarcomas de Ewing constituyen menos de 1% de las lesiones malignas del cuello uterino. A pesar de su baja prevalencia y pocos casos reportados en la bibliografía, debe considerarse en el diagnóstico diferencial de tumoraciones ginecológicas.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  BACKGROUND: Primitive neuroectodermal tumors originate from mesenchymal progenitor cells and are part of various neoplasms, known as the Ewing family tumors. Its expression in the female reproductive system (mainly in the ovary and the uterine body) is an exceptional event.  CLINICAL CASE: A 13-year-old patient, who went to the Gynecological Emergency Department of the Hospital de la Mujer de Morelia, Michoacán, with hypermenorrhea of 5 months of evolution, colic pain in the hypogastrium, without improvement despite the use of analgesics; loss of 3 kg in 1 month and affectation to the general state of health. A physical examination was found: abdomen with a tumor of 10 x 10 cm in the pelvic hollow. It was decided to perform exploratory laparotomy with total abdominal hysterectomy, right oophorectomy and left salpingectomy. The pathology study reported a small round and blue cell tumor that affected the bottom of the vaginal sac and cervix. The immunohistochemical study confirmed the diagnosis of Ewing&amp;apos;s sarcoma. The patient was sent to the Oncology state center to receive chemotherapy and radiotherapy; however, it was lost in the follow-up.  CONCLUSIONS: Abnormal uterine bleeding is one of the most frequent reasons for gynecological consultation in adolescents, which associated with some neoplasm is an exceptional event. Ewing sarcomas constitute less than 1% of malignant lesions of the cervix. Despite its low prevalence and few cases reported in the literature, it should be considered in the differential diagnosis of gynecological tumors.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Tumor neuroectodérmico primitivo]]></kwd>
<kwd lng="es"><![CDATA[células progenitoras mesenquimales]]></kwd>
<kwd lng="es"><![CDATA[hipermenorrea]]></kwd>
<kwd lng="es"><![CDATA[sarcoma de Ewing]]></kwd>
<kwd lng="es"><![CDATA[adolescente]]></kwd>
<kwd lng="en"><![CDATA[Primitive neuroectodermal tumor]]></kwd>
<kwd lng="en"><![CDATA[Mesenchymal progenitor cells]]></kwd>
<kwd lng="en"><![CDATA[Hypermenorrhea]]></kwd>
<kwd lng="en"><![CDATA[Ewing sarcoma]]></kwd>
<kwd lng="en"><![CDATA[Adolescents]]></kwd>
</kwd-group>
</article-meta>
</front><back>
<ref-list>
<ref id="B1">
<label>1</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Elizalde]]></surname>
<given-names><![CDATA[CR]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Primitive neuroectodermal tumor of the uterus]]></article-title>
<source><![CDATA[Gynecol Oncol Rep]]></source>
<year>2016</year>
<volume>18</volume>
<page-range>25-8</page-range></nlm-citation>
</ref>
<ref id="B2">
<label>2</label><nlm-citation citation-type="">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Malpica]]></surname>
<given-names><![CDATA[A.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Miscellaneous cervical neoplasm]]></article-title>
<person-group person-group-type="editor">
<name>
<surname><![CDATA[Muter]]></surname>
<given-names><![CDATA[G]]></given-names>
</name>
</person-group>
<source><![CDATA[Pathology of the female reproductive tract]]></source>
<year>2014</year>
<edition>3</edition>
<page-range>275-89</page-range></nlm-citation>
</ref>
<ref id="B3">
<label>3</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Vivas-Flores]]></surname>
<given-names><![CDATA[CI]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Sarcoma de Ewing extraóseo de origen ginecológico: tumor neuroectodérmico primitivo de localización infrecuente. Reporte de caso y revisión de la literatura]]></article-title>
<source><![CDATA[Rev Colombiana Obstet Ginecol]]></source>
<year>2017</year>
<volume>68</volume>
<numero>2</numero>
<issue>2</issue>
<page-range>135-41</page-range></nlm-citation>
</ref>
<ref id="B4">
<label>4</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Mashriqi]]></surname>
<given-names><![CDATA[Nazia]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Ewing´s sarcoma of the cervix, a diagnostic dilemma: a case report and review of the literature]]></article-title>
<source><![CDATA[J Med Case Rep]]></source>
<year>2015</year>
<volume>9</volume>
<page-range>255</page-range></nlm-citation>
</ref>
<ref id="B5">
<label>5</label><nlm-citation citation-type="">
<person-group person-group-type="author">
<name>
<surname><![CDATA[McCluggage]]></surname>
<given-names><![CDATA[WG.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Practical biomarkers for female genital tract lesions]]></article-title>
<person-group person-group-type="editor">
<name>
<surname><![CDATA[Muter]]></surname>
<given-names><![CDATA[G]]></given-names>
</name>
</person-group>
<source><![CDATA[Pathology of the female reproductive tract]]></source>
<year>2014</year>
<edition>3</edition>
<page-range>828-45</page-range></nlm-citation>
</ref>
<ref id="B6">
<label>6</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Yousefi]]></surname>
<given-names><![CDATA[Z]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Peripheral primitive neuroectodermal tumor of the pelvis]]></article-title>
<source><![CDATA[Iran J Medi Sci]]></source>
<year>2014</year>
<volume>39</volume>
<page-range>71-4</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
