<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0186-4866</journal-id>
<journal-title><![CDATA[Medicina interna de México]]></journal-title>
<abbrev-journal-title><![CDATA[Med. interna Méx.]]></abbrev-journal-title>
<issn>0186-4866</issn>
<publisher>
<publisher-name><![CDATA[Edición y Farmacia S.A. de C.V.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0186-48662018000500002</article-id>
<article-id pub-id-type="doi">10.24245/mim.v34i5.1778</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Síndrome de Guillain-Barré concomitante con infección por virus Zika]]></article-title>
<article-title xml:lang="en"><![CDATA[Guillain-Barre syndrome associated with Zika virus infection.]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ramírez-Rayón]]></surname>
<given-names><![CDATA[Erick M]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ávalos-Ríos]]></surname>
<given-names><![CDATA[Javier M]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[García-Jiménez]]></surname>
<given-names><![CDATA[Francisco J]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Blancas-Cervantes]]></surname>
<given-names><![CDATA[José M]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Añorve-Clavel]]></surname>
<given-names><![CDATA[David]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[García-Cuevas]]></surname>
<given-names><![CDATA[Enrique]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Matadamas-Hernández]]></surname>
<given-names><![CDATA[Norberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[López-Velázquez]]></surname>
<given-names><![CDATA[Diana F]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital General de Acapulco  ]]></institution>
<addr-line><![CDATA[Acapulco de Juárez Guerrero]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital General de Acapulco  ]]></institution>
<addr-line><![CDATA[Acapulco de Juárez Guerrero]]></addr-line>
<country>México</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital General de Acapulco  ]]></institution>
<addr-line><![CDATA[Acapulco de Juárez Guerrero]]></addr-line>
<country>México</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Hospital General de Acapulco  ]]></institution>
<addr-line><![CDATA[Acapulco de Juárez Guerrero]]></addr-line>
<country>México</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Hospital General de Acapulco  ]]></institution>
<addr-line><![CDATA[Acapulco de Juárez Guerrero]]></addr-line>
<country>México</country>
</aff>
<aff id="Af6">
<institution><![CDATA[,Hospital General de Acapulco  ]]></institution>
<addr-line><![CDATA[Acapulco de Juárez Guerrero]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>10</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>10</month>
<year>2018</year>
</pub-date>
<volume>34</volume>
<numero>5</numero>
<fpage>667</fpage>
<lpage>677</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0186-48662018000500002&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0186-48662018000500002&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0186-48662018000500002&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  OBJETIVOS Comunicar una serie de casos de síndrome de Guillain-Barré y describir las características clínicas de una posible asociación con infección previa por virus Zika.  MATERIAL Y MÉTODO  Estudio descriptivo de serie de casos en el que se recolectaron datos clínicos, bioquímicos y demográficos de los pacientes con síndrome de Guillain-Barré tratados en el Hospital General Acapulco con antecedente reciente de síndrome viral agudo sospechoso de infección por virus Zika, del 24 de julio al 24 de agosto de 2016, con realización de estudio de líquido cefalorraquídeo y comprobación de disociación albúmino-citológica. Se estableció diagnóstico de certeza de síndrome de Guillain-Barré según los criterios de Asbury-Cornblath y Brighton.  RESULTADOS Se estudiaron 10 pacientes con síndrome de Guillain-Barré y antecedente reciente de síndrome viral agudo compatible con infección por virus Zika; la edad media de los sujetos en estudio fue de 47.8 años, 4 eran hombres. Los déficits motor y sensitivo sobrevinieron en una mediana de 4.5 y 4.3 días, respectivamente, después del inicio de los síntomas de infección viral. Hubo complicaciones, como neumonía asociada con ventilación mecánica, infección de vías urinarias en tres casos y disautonomía en dos casos.  CONCLUSIONES  Todos los casos de este brote de síndrome de Guillain-Barré tenían antecedente reciente de infección sospechosa por virus Zika, lo que refuerza la evidencia existente de la asociación entre el síndrome de Guillain-Barré y la infección por virus Zika.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  OBJECTIVES To communicate a series of cases of Guillain-Barre syndrome and to describe the clinical characteristics related to a possible association with previous infection due to Zika virus.  MATERIAL AND METHOD  A descriptive study of series of cases in which clinical, biochemical and demographic data were collected from patients with Guillain-Barre syndrome treated at the Hospital General Acapulco with a recent history of acute viral syndrome suspected of infection due to Zika virus, performed from July 24 to August 24, 2016, with conducting study of cerebrospinal fluid and ascertainment of cytological albuminous dissociation. A certainty diagnosis was established for Guillain-Barre syndrome according to the criteria of Asbury-Cornblath and Brighton.  RESULTS  Ten patients with GBS and a recent history of acute viral syndrome compa-tible with Zika virus infection were included. The mean age was 47.8 years, 4 were male. The motor and sensitive deficits were developed at a median of 4.5 and 4.3 days, respectively after the onset of symptoms of viral infection. The complications found were ventilator-associated pneumonia, urinary tract infection and dysautonomia.  CONCLUSIONS  All cases of this outbreak of Guillain-Barre syndrome had a recent history of suspected infection due to Zika virus, reinforcing the evidence for the association between Guillain-Barre syndrome and infection due to Zika virus.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Virus Zika]]></kwd>
<kwd lng="es"><![CDATA[síndrome de Guillain-Barré]]></kwd>
<kwd lng="en"><![CDATA[Zika virus]]></kwd>
<kwd lng="en"><![CDATA[Guillain-Barre syndrome]]></kwd>
</kwd-group>
</article-meta>
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