<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2448-9190</journal-id>
<journal-title><![CDATA[Revista alergia México]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. alerg. Méx.]]></abbrev-journal-title>
<issn>2448-9190</issn>
<publisher>
<publisher-name><![CDATA[Colegio Mexicano de Inmunología Clínica y Alergia A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2448-91902024000300212</article-id>
<article-id pub-id-type="doi">10.29262/ram.v71i3.1383</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Aspergilosis broncopulmonar alérgica en un paciente con diabetes mellitus como único factor de riesgo]]></article-title>
<article-title xml:lang="en"><![CDATA[Allergic bronchopulmonary aspergillosis in a patient with diabetes mellitus as the only risk factor]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hernández-Solís]]></surname>
<given-names><![CDATA[Alejandro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Velázquez-Sámano]]></surname>
<given-names><![CDATA[Guillermo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Apolinar-Juárez]]></surname>
<given-names><![CDATA[Verónica]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mojica Jaimes]]></surname>
<given-names><![CDATA[Eliasib]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Serna Valle]]></surname>
<given-names><![CDATA[Fryda Jareth]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Velazquez Gachuz]]></surname>
<given-names><![CDATA[Yutzil Merari]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Servicio de Neumología y Cirugía de Tórax  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital General de México Dr. Eduardo Liceaga  ]]></institution>
<addr-line><![CDATA[Ciudad de México México]]></addr-line>
<country>México</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad Anáhuac México  ]]></institution>
<addr-line><![CDATA[Ciudad de México México]]></addr-line>
<country>México</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Universidad Nacional Autónoma de México Facultad de Estudios Superiores Iztacala ]]></institution>
<addr-line><![CDATA[Tlalnepantla México]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2024</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2024</year>
</pub-date>
<volume>71</volume>
<numero>3</numero>
<fpage>212</fpage>
<lpage>215</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2448-91902024000300212&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2448-91902024000300212&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2448-91902024000300212&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Antecedentes:  La aspergilosis broncopulmonar alérgica es una enfermedad poco frecuente, ocasionada por una reacción de hipersensibilidad a Aspergillus fumigatus, caracterizada por infiltrados pulmonares, bronquiectasias y aumento de la concentración de eosinófilos en la sangre periférica.  Reporte de caso: Paciente masculino de 42 años, con antecedente de diabetes mellitus, con mal apego al tratamiento, que acudió al servicio de Urgencias por disnea rápidamente progresiva e hipoxemia grave. Se evidenció neumonía y derrame pleural bilateral; los estudios de laboratorio reportaron: HbA1c 9.4%, eosinófilos 3650 células/mL, e IgE sérica para Aspergillus fumigatus 0.84 UI/mL. Se inició tratamiento con oxígeno suplementario, prednisona e itraconazol, con reacción clínica y radiológica satisfactorias.  Conclusión: Las micosis invasivas suponen una mortalidad del 21 al 80%, sobre todo en pacientes inmunocomprometidos, y no suelen informarse en quienes padecen diabetes mellitus. La prevalencia de colonización fúngica en pacientes con y sin diabetes se ha descrito en 37 vs 4.7%, respectivamente.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Background: Allergic bronchopulmonary aspergillosis is a rare entity, caused by a hypersensitivity reaction of the immune system to Aspergillus fumigatus, characterized by the presence of pulmonary infiltrates, bronchiectasis and increased eosinophils in peripheral blood.  Case report: 42-year-old male with diabetes mellitus, with poor adherence to treatment, went to the emergency room due to rapidly progressive dyspnea and severe hypoxemia, pneumonia and bilateral pleural effusion were evident, laboratory studies reported, HbA1c 9.4%, eosinophils 3650 cells/mL, serum IgE for Aspergillus fumigatus 0.84 IU/mL. Treatment was started with supplemental oxygen, prednisone and itraconazole, to which the patient showed clinical and radiological improvement.  Conclusion: Invasive mycoses have a mortality of 21 to 80%, frequently in immunocompromised patients, they are usually not described in patients with diabetes mellitus; The prevalence of fungal colonization among diabetic patients has been described as 37% compared to 4.7% in non-diabetic patients.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Aspergilosis broncopulmonar alérgica]]></kwd>
<kwd lng="es"><![CDATA[Diabetes mellitus]]></kwd>
<kwd lng="es"><![CDATA[Aspergillus fumigatus]]></kwd>
<kwd lng="en"><![CDATA[Allergic bronchopulmonary aspergillosis]]></kwd>
<kwd lng="en"><![CDATA[Diabetes mellitus]]></kwd>
<kwd lng="en"><![CDATA[Aspergillus fumigatus]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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