<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2448-5691</journal-id>
<journal-title><![CDATA[Mundo nano. Revista interdisciplinaria en nanociencias y nanotecnología]]></journal-title>
<abbrev-journal-title><![CDATA[Mundo nano]]></abbrev-journal-title>
<issn>2448-5691</issn>
<publisher>
<publisher-name><![CDATA[Universidad Nacional Autónoma de México, Instituto de Ciencias Aplicadas y Tecnología]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2448-56912013000100063</article-id>
<article-id pub-id-type="doi">10.22201/ceiich.24485691e.2013.10.50965</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Avances e implicaciones éticosociales de la nanomedicina: una revisión desde el caso del cáncer cerebral]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Delgado Ramos]]></surname>
<given-names><![CDATA[Gian Carlo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hernández Burciaga]]></surname>
<given-names><![CDATA[Luis Alberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Nacional Autónoma de México Centro de Investigaciones Interdisciplinarias en Ciencias y Humanidades ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Nacional Autónoma de México Facultad de Filosofía y Letras ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2013</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2013</year>
</pub-date>
<volume>6</volume>
<numero>10</numero>
<fpage>63</fpage>
<lpage>85</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2448-56912013000100063&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2448-56912013000100063&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2448-56912013000100063&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: Entre las aplicaciones de la nanotecnología más prometedoras y dinámicas están aquellas del sector salud. Destacan las investigaciones en enfermedades como el cáncer, VIH sida, diabetes, osteoartritis, enfermedades degenerativas y desordenes cardiovasculares y nerviosos. El presente texto abre con una breve introducción acerca del estado actual de la investigación y desarrollo de la nanotecnología y sus aplicaciones médicas, particularmente desde una perspectiva económica. A continuación, indaga con mayor detenimiento el caso del cáncer y en específico del cáncer cerebral, los retos de su diagnóstico y tratamiento y el potencial de la nanotecnología para confrontarlos. A partir de una revisión de más de tres mil artículos registrados en PubMed se ofrece un análisis sobre el avance de la investigación en cáncer y cáncer cerebral en lo que va del siglo XXI, tanto en lo que se refiere al espectro de tipos de cáncer como de estructuras nanométricas empleadas. Se cierra con una reflexión tanto de los potenciales riesgos asociados a la exposición directa a nanomateriales, como de las implicaciones sociales y éticas del avance de la nanomedicina. Con la inclusión de una propuesta normativa de modelo integral de gestión y distribución del riesgo, se argumenta que es oportuno estimular y regular responsable y democráticamente al sector de la nanomedicina y en sí de las nanotecnologías como un todo a modo de minimizar eventuales costos y riesgos innecesarios.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: Health applications are among the most promising and dynamic of nanotechnology innovation. To highlight are those focused on cancer, HIV-AIDS, diabetes, osteoarthritis, degenerative diseases, and cardiovascular and nervous disorders. This paper deals with nanoapplications for brain cancer. It starts with a brief introduction about current state of research and development of nanotechnology and its medical applications, particularly from an economic perspective. It then briefly presents cancer and brain cancer diseases, current challenges of diagnosis and treatment and nanotechnology potential to solve them. After a review of more than three thousand papers registered in PubMed database (from 2000 to 2013), an analysis of the progress of nanorelated research in cancer is offered. It includes a general description of types of cancers, including brain cancer, and nanostructures currently being studied. Finally, a reflection on potential risks associated with direct exposure to nanomaterials, as well as on social and ethical implications of the progress of nanomedicine is presented. By outlining a normative model of an integrated management and distribution of risk, we argue the relevance of democratically and responsibly promoting and regulating nanotechnology in general and nanomedicine in particular; all with the purpose of minimizing eventual costs and unnecessary risks.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[nanomedicina]]></kwd>
<kwd lng="es"><![CDATA[cáncer cerebral]]></kwd>
<kwd lng="es"><![CDATA[aspectos sociales]]></kwd>
<kwd lng="es"><![CDATA[ética]]></kwd>
<kwd lng="es"><![CDATA[regulación]]></kwd>
<kwd lng="en"><![CDATA[nanomedicine]]></kwd>
<kwd lng="en"><![CDATA[brain cancer]]></kwd>
<kwd lng="en"><![CDATA[social aspects]]></kwd>
<kwd lng="en"><![CDATA[ethical regulation]]></kwd>
</kwd-group>
</article-meta>
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