<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1870-7203</journal-id>
<journal-title><![CDATA[Acta médica Grupo Ángeles]]></journal-title>
<abbrev-journal-title><![CDATA[Acta méd. Grupo Ángeles]]></abbrev-journal-title>
<issn>1870-7203</issn>
<publisher>
<publisher-name><![CDATA[Grupo Ángeles, Servicios de Salud]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1870-72032017000100020</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Respuesta al tratamiento oncoespecífico en carcinomas no microcíticos etapa IIIA no quirúrgica]]></article-title>
<article-title xml:lang="en"><![CDATA[Response to the oncospecific treatment in non-microcytic carcinomas in non-surgical stage IIIa]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Díaz Garrido]]></surname>
<given-names><![CDATA[Drialis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[León Valdivies]]></surname>
<given-names><![CDATA[Yusbiel J]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Fernández García]]></surname>
<given-names><![CDATA[Sergio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Díaz Toledo]]></surname>
<given-names><![CDATA[Manuel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez de la Osa]]></surname>
<given-names><![CDATA[Reynaldo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Osés Herrera]]></surname>
<given-names><![CDATA[Liliana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Benéfico Jurídico Servicio de Neumología ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Gustavo Aldereguía Lima Servicio de Medicina Interna ]]></institution>
<addr-line><![CDATA[Cienfuegos ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital Benéfico Jurídico Servicio de Oncología ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Hospital Benéfico Jurídico Servicio de Imagenología ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Universidad de Ciencias Médicas  ]]></institution>
<addr-line><![CDATA[Cienfuegos ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>02</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>02</month>
<year>2017</year>
</pub-date>
<volume>15</volume>
<numero>1</numero>
<fpage>20</fpage>
<lpage>24</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S1870-72032017000100020&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S1870-72032017000100020&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S1870-72032017000100020&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: El cáncer de pulmón de células no pequeñas incluye los tumores malignos más frecuentes del pulmón. Se realizó un estudio descriptivo, ambispectivo para evaluar la evolución clínica y radiológica en 61 pacientes con cáncer de pulmón de células no pequeñas en estadio IIIA no quirúrgico, tratados con poliquimioterapia y/o radioterapia en el Hospital Benéfico Jurídico en el periodo comprendido entre enero de 2011 y diciembre de 2013. Predominaron los individuos del sexo masculino (70.5%) con edad mayor de 60 años (63.9%). El tratamiento oncoespecífico redujo significativamente la pérdida de peso (52.5% frente a 13.1%, p = 0.007), el dolor torácico (55.7% frente a 27.9%, p = 0.015) y la expectoración (31.1% frente a 18.0%, p = 0.043). Después del tratamiento oncoespecífico, se encontró un empeoramiento progresivo del estado funcional (p = 0.015). Más de la mitad de los sujetos (57.4%) estaban estables (27.8%) o con alguna respuesta objetiva antitumoral (29.6%). No obstante, el 42.6% se hallaba en progresión de la enfermedad. Aunque el tratamiento oncoespecífico no quirúrgico en personas con cáncer de pulmón no microcítico en etapa IIIA produce una mejoría significativa de algunos síntomas, los pacientes empeoran progresivamente su estado funcional, con una baja respuesta objetiva antitumoral.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Summary: Non-small-cell lung cancer includes the most frequent malignant tumors of the lung. A descriptive, ambispective study was carried out to evaluate the clinical and radiological evolution of 61 patients with non-surgical stage IIIA non-small-cell lung cancer, treated with polychemotherapy and/or radiotherapy in the Hospital Benéfico Jurídico in the period between January 2011 and December 2013. Male subjects (70.5%) 60 years and older (63.9%) prevailed. Oncospecific treatment significantly reduced weight loss (52.5% vs. 13.1%, p = 0.007), thoracic pain (55.7% vs. 27.9%, p = 0.015) and expectoration (31.1% vs. 18.0%, p = 0.043). After the oncospecific treatment, a progressive worsening of the functional status was found (p = 0.015). More than half of the patients (57.4%) were stable (27.8%) or with some objective antitumor response (29.6%). Nevertheless, 42.6% were in progression of the disease. Although non-surgical oncospecific treatment results in a significant improvement of some symptoms in patients with stage IIIA non-small-cell lung cancer, their functional status worsens progressively, with a low objective antitumor response.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Tratamiento oncoespecífico]]></kwd>
<kwd lng="es"><![CDATA[etapa IIIa]]></kwd>
<kwd lng="es"><![CDATA[cáncer de pulmón de células no pequeñas]]></kwd>
<kwd lng="en"><![CDATA[Oncospecific treatment]]></kwd>
<kwd lng="en"><![CDATA[stage IIIA]]></kwd>
<kwd lng="en"><![CDATA[non-small-cell lung cancer]]></kwd>
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<surname><![CDATA[Michaud]]></surname>
<given-names><![CDATA[GC]]></given-names>
</name>
<name>
<surname><![CDATA[Balekian]]></surname>
<given-names><![CDATA[A]]></given-names>
</name>
</person-group>
<source><![CDATA[Chest]]></source>
<year>2013</year>
<volume>144</volume>
<page-range>1743</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
