Isocordoin Derivatives From the Root Extract of Lonchocarpus xuul

Alejandro Yam–Puc and Luis M. Peña–Rodríguez^{1 *}

¹ Grupo de Química Orgánica, Unidad de Biotecnología, Centro de Investigación Científica de Yucatán, Calle 43 No. 130, Colonia Chuburná, Mérida, Yucatán, México. ^*Responsible author: lmanuel@cicy.mx.

Received October 27, 2008
Accepted February 25, 2009

Abstract

Two natural isocordoin derivatives, dihydroisocordoin (1) and flemistrictin B (2), were isolated from the root extract of Lonchocarpus xuul. Both metabolites were identified on the basis of their spectroscopic data and by comparing them with those reported in the literature.

Key words: Lonchocarpus xuul, Leguminosae, Chalcones, Dihydroisocordoin, Flemistrictin B.

Resumen

Del extracto de la raíz de Lonchocarpus xuul fueron aislados dos derivados naturales de isocordoína, dihidroisocordoína (1) y flemistrictina B (2). Ambos metabolitos fueron identificados con base en sus datos espectroscópicos y por comparación de los mismos con los reportados en la literatura.

Palabras clave: Lonchocarpus xuul, leguminosa, chalcones, dihidroisocordoína, flemistrictina B.

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Acknowledgements

The authors wish to thank Rocío Borges–Argáez for providing an isocordoin–rich fraction for initial purification, and Mirbella Cáceres–Farfán for technical assistance. The results of this investigation are part of the RIBIOFAR–CYTED project. Financial support from FOMIX–Yucatán (grant No. YUC–2006–C05–66262) is also gratefully acknowledged.

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