<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1665-5044</journal-id>
<journal-title><![CDATA[Revista mexicana de neurociencia]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. mex. neurocienc.]]></abbrev-journal-title>
<issn>1665-5044</issn>
<publisher>
<publisher-name><![CDATA[Academia Mexicana de Neurología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1665-50442023000600192</article-id>
<article-id pub-id-type="doi">10.24875/rmn.m23000097</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Bundled care to optimize outcome after intracerebral hemorrhage: action for effective implementation]]></article-title>
<article-title xml:lang="es"><![CDATA[Atención agrupada para optimizar los resultados tras una hemorragia intracerebral: medidas para una aplicación eficaz]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ouyang]]></surname>
<given-names><![CDATA[Menglu]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Anderson]]></surname>
<given-names><![CDATA[Craig S.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
<xref ref-type="aff" rid="A a"/>
<xref ref-type="aff" rid="A3 "/>
<xref ref-type="aff" rid="Af4"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,University of New South Wales Faculty of Medicine George Institute for Global Health]]></institution>
<addr-line><![CDATA[Sydney ]]></addr-line>
<country>Australia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,George Institute for Global Health  ]]></institution>
<addr-line><![CDATA[Beijing ]]></addr-line>
<country>China</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Sydney Health Partners Royal Prince Alfred Hospital Department of Neurology]]></institution>
<addr-line><![CDATA[Sydney ]]></addr-line>
<country>Australia</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Faculty of Medicine Clinica Alemana Universidad del Desarrollo Clinical Research Center ]]></institution>
<addr-line><![CDATA[Santiago ]]></addr-line>
<country>Chile</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2023</year>
</pub-date>
<volume>24</volume>
<numero>6</numero>
<fpage>192</fpage>
<lpage>194</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S1665-50442023000600192&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S1665-50442023000600192&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S1665-50442023000600192&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Patients who experience acute intracerebral hemorrhage (ICH) are not managed with urgency or level of coordinated care as those with acute ischemic stroke. This is largely due to the lack of any proven treatment for ICH, which has led to therapeutic nihilism and a low threshold for the withdrawal of active care in these patients. The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3) is a landmark study which used a novel, quality improvement, implementation design across 122 hospitals in 10 countries, to show that the early intervention of bundled care with time- and target-based metrics, can substantially improve outcomes for patients who suffer ICH. We advocate the widespread adoption of an early bundle of care focused on urgent time-based metrics for the control of elevated blood pressure and other abnormal physiological parameters, and the emergency reversal of anticoagulation, for patients with ICH. Such coordinated interdisciplinary stroke care will optimise the chances of patients all over the world surviving free of major disability after suffering an ICH.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen Los pacientes que sufren una hemorragia intracerebral aguda (HIC) no se tratan con la urgencia ni el nivel de atención coordinada que los que sufren un ictus isquémico agudo. Esto se debe en gran medida a la falta de un tratamiento probado para la HIC, lo que ha llevado a un nihilismo terapéutico y a un umbral bajo para la retirada de los cuidados activos en estos pacientes. El tercer Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3) es un estudio de referencia que utilizó un novedoso diseño de implementación para la mejora de la calidad en 122 hospitales de 10 países, con el fin de demostrar que la intervención temprana de la atención agrupada con métricas basadas en el tiempo y los objetivos puede mejorar sustancialmente los resultados de los pacientes que sufren HIC. Abogamos por la adopción generalizada de un paquete de atención temprana centrado en parámetros urgentes basados en el tiempo para el control de la presión arterial elevada y otros parámetros fisiológicos anormales, y la reversión urgente de la anticoagulación, para pacientes con HIC. Esta atención interdisciplinaria coordinada optimizará las posibilidades de que los pacientes de todo el mundo sobrevivan sin discapacidades graves tras sufrir una HIC.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Intracerebral hemorrhage]]></kwd>
<kwd lng="en"><![CDATA[Protocols]]></kwd>
<kwd lng="en"><![CDATA[Health outcomes]]></kwd>
<kwd lng="en"><![CDATA[Implementation]]></kwd>
<kwd lng="en"><![CDATA[Stroke services]]></kwd>
<kwd lng="es"><![CDATA[Hemorragia intracerebral]]></kwd>
<kwd lng="es"><![CDATA[Protocolos]]></kwd>
<kwd lng="es"><![CDATA[Resultados sanitarios]]></kwd>
<kwd lng="es"><![CDATA[Implementación]]></kwd>
<kwd lng="es"><![CDATA[Servicios de ictus]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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