1405-6666 1405-6666 S1405-66662022000401143 Spain España Spain Spain 00 12 2022 00 12 2022 27 95 1143 1163

2010 5 5 2001 2019 22 1 1 175-94 2007 30 2 2 177-90 2002 17 2 2 129-47 2001 195-207 2015 2015 2013 12 1 1 1985 32 3 3 149-61 2021 2020 315-30 Comisión Europea 2020 2017 12 10 10 589-94 2008 31 ^s2 ^s2 2 153-63 2020 2015 8 2 2 1-17 FEDER CREER 2018 2014 7 3 3 97-24 2010 16 1 1 39-50 2015 2008 31 ^s2 ^s2 2 165-75 2014 7 3 3 84-96 2010 3 1 1 545-52 2019 1 2 2 271-80 2017 6 274-86 2019 17 26 26 219-34 2016 19 3 3 11-24 2014 18 8 8 550-63 Rare Diseases Clinical Research Network 2009 96 1 1 20-6 Instituto de Salud Carlos III 2021 2019 10 1 1 1-19 2019 22 1 1 225-40 Organización Mundial de la Salud 2001 2020 18 2002 63 3 3 223-32 2005 23 2 2 433-48 2018 47 2 2 167-76 2018 36 2 2 365-79 2007 2011 11 1 1 11-23 2011 21 1 1 31-7 2004 13-5 2008 31 ^s2 ^s2 2 5-8 2017 17 17 373-95 1996