<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0484-7903</journal-id>
<journal-title><![CDATA[Revista mexicana de anestesiología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. mex. anestesiol.]]></abbrev-journal-title>
<issn>0484-7903</issn>
<publisher>
<publisher-name><![CDATA[Colegio Mexicano de Anestesiología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0484-79032020000100064</article-id>
<article-id pub-id-type="doi">10.35366/cma201l</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Sedoanalgesia en neonato a base de remifentanyl. En relación con un caso para epiglotopexia]]></article-title>
<article-title xml:lang="en"><![CDATA[Sedoanalgesia in neonate based on remifentanyl. In relation to a case for epiglottopexy]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Madriz-Godoy]]></surname>
<given-names><![CDATA[María Mayela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez-Hernández]]></surname>
<given-names><![CDATA[Eloy]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ortiz-Hernández]]></surname>
<given-names><![CDATA[Enrique Gerardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,OPD Hospital Civil de Guadalajara «Fray Antonio Alcalde»  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,OPD Hospital Civil de Guadalajara «Fray Antonio Alcalde» Servicio de Anestesiología ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,OPD Hospital Civil de Guadalajara «Fray Antonio Alcalde» Servicio de Otorrinolaringología y Cirugía de Cabeza y Cuello ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2020</year>
</pub-date>
<volume>43</volume>
<numero>1</numero>
<fpage>64</fpage>
<lpage>68</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0484-79032020000100064&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0484-79032020000100064&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0484-79032020000100064&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: La etapa neonatal comprende del primer día hasta el día 28 de vida. Se caracteriza por ser una etapa de inmadurez anatómica, fisiológica y metabólica. Por estas características del neonato, los fármacos anestésicos impactan de manera importante en su fisiología respiratoria y cardiovascular; además la farmacocinética se ve modificada por esta inmadurez. La laringomalacia es una de las principales causas de estridor en esta etapa, misma que, dependiendo de la severidad puede requerir manejo quirúrgico, siendo una opción la epiglotopexia. Dicho procedimiento requiere analgesia potente y a su vez la posibilidad de mantener la ventilación espontánea para su adecuada evaluación, mismas que pueden ser alcanzadas con el uso de remifentanyl. Presentamos el caso clínico de un neonato de término de 22 días de vida a quien se le administró remifentanyl como base de la sedoanalgesia para realización de epiglotopexia de manera exitosa. Su potencia analgésica, capacidad de mantener el automatismo ventilatorio y la farmacocinética predecible en el neonato, convierten al remifentanyl en un agente ideal para proporcionar adecuada sedoanalgesia para diferentes procedimientos con un perfil de fácil titulación y de recuperación rápida en el neonato.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract. The neonatal stage comprises from the first day of birth until day 28 of life. It is characterized by being a stage of anatomical, physiological and metabolic immaturity. Due to these characteristics of neonates, anesthetic drugs have an important impact on their respiratory and cardiovascular physiology, and their immaturity on pharmacokinetics. Laryngomalacia is one of the main causes of stridor in this stage, which depending on its severity could require surgical treatment, such as an epiglotopexy. This procedure requires potent analgesia and at the same time the possibility of maintaining spontaneous ventilation for its appropriate evaluation. This can be achieved with the use of remifentanyl. We present the clinical case of a term neonate of 22 days of age who we administered Remifentanyl as the basis of sedoanalgesia for the successful completion of an epiglotopexy. Its analgesic potency, ability to maintain ventilatory automatism and predictable pharmacokinetics in the neonate, makes it an ideal agent to provide adecuate sedoanalgesia for different procedures with an easy titration profile and rapid recovery in the neonate.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Remifentanyl]]></kwd>
<kwd lng="es"><![CDATA[neonato]]></kwd>
<kwd lng="es"><![CDATA[recién nacido]]></kwd>
<kwd lng="es"><![CDATA[epiglotopexia]]></kwd>
<kwd lng="es"><![CDATA[sedoanalgesia]]></kwd>
<kwd lng="es"><![CDATA[anestesia]]></kwd>
<kwd lng="en"><![CDATA[Remifentanyl]]></kwd>
<kwd lng="en"><![CDATA[neonate]]></kwd>
<kwd lng="en"><![CDATA[newborn]]></kwd>
<kwd lng="en"><![CDATA[epiglottopexy]]></kwd>
<kwd lng="en"><![CDATA[sedoanalgesia]]></kwd>
<kwd lng="en"><![CDATA[anesthesia]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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