<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0300-9041</journal-id>
<journal-title><![CDATA[Ginecología y obstetricia de México]]></journal-title>
<abbrev-journal-title><![CDATA[Ginecol. obstet. Méx.]]></abbrev-journal-title>
<issn>0300-9041</issn>
<publisher>
<publisher-name><![CDATA[Federación Mexicana de Colegios de Obstetricia y Ginecología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0300-90412020000300002</article-id>
<article-id pub-id-type="doi">10.24245/gom.v88i3.3727</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Factores de riesgo modificables del cáncer de mama: una comparación entre mujeres menores y mayores de 40 años]]></article-title>
<article-title xml:lang="en"><![CDATA[Modifiable risk factors for breast cancer: a comparison between women younger and older than 40 years-old]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Moncada-Madrazo]]></surname>
<given-names><![CDATA[Mariana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Aranda-Gutierrez]]></surname>
<given-names><![CDATA[Alejandro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Isojo-Gutiérrez]]></surname>
<given-names><![CDATA[Rigoberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Issa-Villarreal]]></surname>
<given-names><![CDATA[María Emilia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Elizondo-Granillo]]></surname>
<given-names><![CDATA[Carlos]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ramos-Reyes]]></surname>
<given-names><![CDATA[Álvaro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Garza-Krause]]></surname>
<given-names><![CDATA[Evelyn]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Magallanes-Garza]]></surname>
<given-names><![CDATA[Gerardo I]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Soto-Fuenzalida]]></surname>
<given-names><![CDATA[Gonzalo Andrés]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Tecnológico y de Estudios Superiores de Monterrey  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Instituto Tecnológico y de Estudios Superiores de Monterrey Departamento de Ciencias Clínicas ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2020</year>
</pub-date>
<volume>88</volume>
<numero>3</numero>
<fpage>131</fpage>
<lpage>138</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0300-90412020000300002&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0300-90412020000300002&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0300-90412020000300002&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  OBJETIVO:  Analizar la repercusión diferencial de los principales factores de riesgo modificables asociados con el cáncer de mama en pacientes menores y mayores de 40 años.  MATERIALES Y MÉTODOS:  Estudio de cohorte, retrospectivo, observacional y descriptivo. Se reunió la información de las pacientes con diagnóstico o tratamiento de cáncer de mama atendidas en un centro hospitalario del Noreste de México entre enero de 2016 y diciembre de 2017. La asociación entre las distintas variables y los grupos etarios se determinó con la prueba de la &#967;2 de Pearson y se consideraron estadísticamente significativos los valores con p &lt; 0.05.  RESULTADOS:  Se revisaron 524 expedientes clínicos de pacientes con cáncer de mama, con límites de edad entre 22 y 99 y se seleccionaron las menores de 40 años (n = 75) que representaron 14.31% del total de las pacientes atendidas, porcentaje que coincide con la prevalencia de cáncer de mama en mujeres jóvenes reportada en la bibliografía mexicana. Se encontró un efecto similar en el riesgo de padecer cáncer de mama entre ambos grupos con los siguientes factores de riesgo modificables: nuliparidad, tabaquismo, consumo de alcohol, sedentarismo y anticoncepción hormonal. La obesidad (IMC superior a 30) tuvo mayor repercusión en mujeres de más de 40 años.  CONCLUSIÓN:  La prevalencia de cáncer de mama en las pacientes jóvenes fue del doble de lo reportado en el ámbito internacional. Es necesario el control de peso en mujeres menores de 40 años, que permita reducir la incidencia del cáncer de mama triple negativo en esta población. Asimismo, se recomienda el control de los otros factores de riesgo modificables porque, aunque no parecen afectar significativamente a las mujeres jóvenes, su control tiene una repercusión positiva en la prevención del cáncer de mama en todos los grupos etarios.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  OBJECTIVE:  To analyze the differential impact of the main modifiable risk factors associated with breast cancer among patients younger than 40 years of age.  MATERIALS AND METHODS:  Cohort, retrospective, observational and descriptive study. The information of the patients with diagnosis or treatment of breast cancer treated in a hospital in Northeast Mexico between January 2016 and December 2017 was collected. The association between the different variables and the age groups was determined with the test of Pearson&#8217;s &#967;2 and the values p &lt; 0.05 were considered statistically significant.  RESULTS:  524 clinical records of patients with breast cancer were reviewed, with age limits between 22 and 99 years. From this group, patients under 40 years of age (n = 75) were selected, representing 14.31% of the total number of patients treated, a percentage that coincides with the prevalence of breast cancer in young women reported in the Mexican literature. A similar impact was found on the risk of breast cancer between both groups with the following modifiable risk factors: nulliparity, smoking, alcohol consumption, sedentary lifestyle and hormonal contraception. Obesity (BMI &#8805; 30) had a greater impact on women &#8805; 40 years.  CONCLUSION:  The prevalence of breast cancer in young patients was double what was reported internationally. Weight control is necessary in women under 40 years of age, which allows reducing the incidence of triple negative breast cancer in this population. Likewise, the control of the other modifiable risk factors is recommended because, although they do not seem to significantly affect young women, their control has a positive impact on the prevention of breast cancer in all age groups.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Cáncer de mama]]></kwd>
<kwd lng="es"><![CDATA[factores de riesgo]]></kwd>
<kwd lng="es"><![CDATA[mujeres menores de 40 años]]></kwd>
<kwd lng="es"><![CDATA[México]]></kwd>
<kwd lng="es"><![CDATA[cáncer de mama triple negativo]]></kwd>
<kwd lng="es"><![CDATA[consumo de alcohol]]></kwd>
<kwd lng="es"><![CDATA[obesidad]]></kwd>
<kwd lng="en"><![CDATA[Breast cancer]]></kwd>
<kwd lng="en"><![CDATA[Risk factors]]></kwd>
<kwd lng="en"><![CDATA[40 years of age]]></kwd>
<kwd lng="en"><![CDATA[Mexico]]></kwd>
<kwd lng="en"><![CDATA[Triple Negative Breast Neoplasms]]></kwd>
<kwd lng="en"><![CDATA[Alcohol Drinking]]></kwd>
<kwd lng="en"><![CDATA[Obesity]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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