<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0028-3746</journal-id>
<journal-title><![CDATA[Neumología y cirugía de tórax]]></journal-title>
<abbrev-journal-title><![CDATA[Neumol. cir. torax]]></abbrev-journal-title>
<issn>0028-3746</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Mexicana de Neumología y Cirugía de Tórax; Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas; Sociedad Cubana de Neumología; Sociedad Paraguaya de Neumología; Sociedad Boliviana de Neumología.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0028-37462017000200084</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Diagnóstico de tuberculosis extrapulmonar por cultivo]]></article-title>
<article-title xml:lang="en"><![CDATA[Diagnostic the extrapulmonary tuberculosis by culture]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Palacios-Marmolejo]]></surname>
<given-names><![CDATA[Anastacio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Luna-Ramírez]]></surname>
<given-names><![CDATA[Gabriela de]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ornelas-Perea]]></surname>
<given-names><![CDATA[Mariana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Herrera-Leandro]]></surname>
<given-names><![CDATA[Daniel Alejandro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ortiz-Palos]]></surname>
<given-names><![CDATA[Mónica]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Silva-Menchaca]]></surname>
<given-names><![CDATA[Juan José]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto de Servicios de Salud del Estado de Aguascalientes Laboratorio Estatal de Salud Pública Departamento de Microbiología]]></institution>
<addr-line><![CDATA[Aguascalientes ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Cuauhtémoc Escuela de Medicina Plantel Aguascalientes]]></institution>
<addr-line><![CDATA[Aguascalientes ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2017</year>
</pub-date>
<volume>76</volume>
<numero>2</numero>
<fpage>84</fpage>
<lpage>90</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0028-37462017000200084&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0028-37462017000200084&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0028-37462017000200084&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  Antecedentes:  La tuberculosis es una enfermedad infectocontagiosa causada principalmente por Mycobacterium tuberculosis (M. tuberculosis), que se puede manifestar en pulmonar (TBP) en el 85% de los casos y el resto en forma extrapulmonar (TBEP). Actualmente es un problema de salud pública y el mejor diagnóstico a nivel laboratorio es el cultivo (diagnóstico estándar de referencia).  Material y métodos:  Se realizó un estudio observacional y retrospectivo basado en el aislamiento de M. tuberculosis en muestras extrapulmonares por cultivo, utilizando el equipo BACTEC MGIT-960 y pruebas de identificación y farmacosensibilidad.  Resultados:  Se cultivaron 654 muestras obteniendo una positividad del 5.5% (36 aislamientos), 7 de pacientes menores de 15, y 3 en pacientes mayores de 60 años. De acuerdo al órgano/tejido afectado: 30.6% piel, 27.8% renal, 11.1% cavidad torácica (excepto pulmón), aparato digestivo y articulaciones, respectivamente, y 8.3% del sistema nervioso central. Del total de los aislamientos del complejo M. tuberculosis se incluyó una cepa de M. bovis. En cuanto a los resultados de farmacosensibilidad se obtuvo una sensibilidad del 100% para etambutol y rifampicina, del 94.5% para isoniacida y 44.0% para pirazinamida.  Conclusiones:  Se demostró la importancia del cultivo para el diagnóstico y pruebas de farmacosensibilidad en pacientes con sospecha de TBEP.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract:  Background:  Tuberculosis is an infectious-contagious disease, mainly caused by Mycobacterium tuberculosis, which can be manifested in pulmonary (PTB) in 85% of cases and the rest in extra pulmonary form (EPTB), currently it is a public health problem and the best laboratory diagnosis is the culture (standard reference for diagnosis).  Material and methods:  An observational and retrospective study was carried out, based on the isolation of M. tuberculosis, in extrapulmonary samples by culture using the BACTEC MGIT-960 equipment, as well as the identification and drug-sensitivity tests for each of the isolates.  Results:  654 samples were cultured, obtaining a positivity of 5.5% (36 isolations), 7 of them in patients younger than 15 years old and 3 in patients older than 60 years old, according to the organ/tissue affected: 30.6% skin, 27.8% renal, 11.1% thoracic cavity (except lung), digestive system and joints, respectively, and 8.3% CNS (central nervous system). From the total isolates of the M. tuberculosis complex includes a strain of M. bovis. Regarding the results of drug-sensitivity, 100% sensitivity was obtained for etambutol and rifampicin, 94.5% for isoniacin and 44.0% for pirazinamide.  Conclusions:  The importance of culture for the diagnosis and tests of drug-sensitivity in patients with suspected EPTB was demonstrated.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Cultivo]]></kwd>
<kwd lng="es"><![CDATA[M. tuberculosis]]></kwd>
<kwd lng="es"><![CDATA[farmacosensibilidad]]></kwd>
<kwd lng="es"><![CDATA[tuberculosis extrapulmonar]]></kwd>
<kwd lng="en"><![CDATA[Culture]]></kwd>
<kwd lng="en"><![CDATA[M. tuberculosis]]></kwd>
<kwd lng="en"><![CDATA[drug sensitivity]]></kwd>
<kwd lng="en"><![CDATA[extrapulmonary tuberculosis]]></kwd>
</kwd-group>
</article-meta>
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